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Query: VAMP8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VAMP8 0 1.983 0.400 -0.770

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VAMP8 Phosphorylation S55 0.753 0.547 _NKTEDLEATS(ph)EHFK_
VAMP8 Ubiquitylation K47 0.262 0.420 _NK(gl)TEDLEATSEHFK_
VAMP8 Ubiquitylation K59 -0.052 _NKTEDLEATSEHFK(gl)TTSQK_

Background Information for VAMP8:


Pubmed-VAMP8 »
Uniprot-VAMP8 »
Biogrid-VAMP8 »
ProteomicsDB-VAMP8 »

Tumorportal-VAMP8 »
COSMIC-VAMP8 »
GenomeRNAi-VAMP8 »
Genecards-VAMP8


Protein-protein Interactions for VAMP8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SNAP29 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VAMP8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Synaptobrevin IPR001388 0
Category members Synaptobrevin/VAMP_met/fun IPR016444 0


Protein complexes (CORUM database) featuring VAMP8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 874 SNARE complex (VAMP3, VAMP4, VAMP8, STX6) Database 0.62
Category members Corum 1169 SNARE complex (STX4, VAMP8, VAMP3, SNAP23) Database 0.32


Categories featuring VAMP8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_1261 KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 0 1.52
Category members GO Category GO:0006906 vesicle fusion Database 1.28
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members GO Category GO:0061025 membrane fusion Database 0.93
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0006892 post-Golgi vesicle-mediated transport Database 0.74
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0031201 SNARE complex Database 0.49
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members Pathway Pathway_473 REACTOME_LYSOSOME_VESICLE_BIOGENESIS 0 0.13
Category members GO Category GO:0030141 secretory granule Database 0.11
Category members GO Category GO:0019905 syntaxin binding Database 0.05
Category members GO Category GO:0030667 secretory granule membrane Database 0.05
Category members GO Category GO:0000046 autophagic vacuole fusion Database 0.04
Category members GO Category GO:0030100 regulation of endocytosis Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0


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