bioLOGIC-db

bioLOGIC Data

Query: USP1

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
USP1	1	0.023	2.430	-1.190

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
USP1	Phosphorylation	S67	-0.170	0.304	_ASEIDQVVPAAQSS(ph)PINCEK_
USP1	Phosphorylation	S66		0.045	_ASEIDQVVPAAQS(ph)SPINCEK_
USP1	Phosphorylation	S475	-1.080	-0.086	_REDFQDISVPVQEDELSKVEESSEIS(ph)PEPK_
USP1	Ubiquitylation	K689	0.173	-1.509	_ASNPDK(gl)VASTAFAENR_
USP1	Phosphorylation	S42	1.055		_ALDFTDS(ph)QENEEK_

Pubmed-USP1 »

ProteomicsDB-USP1 »

COSMIC-USP1 »

Genecards-USP1

Protein-protein Interactions for USP1

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait BAG6;BAT3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait C1orf63	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CERK	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait DCTN3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KATNA1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KPNA1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PIP4K2C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SGTB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SORT1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SYNCRIP	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TOR1AIP1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait USP43	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait WDR48	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RAD51AP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait USP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in USP1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	UCH/PAN2	IPR028889	0.62
Category members	Peptidase_C19_UCH	IPR001394	0.53

Protein complexes (CORUM database) featuring USP1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring USP1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005654	nucleoplasm	Database	INF
Category members	GO Category	GO:0006281	DNA repair	Database	INF
Category members	Pathway	Pathway_338	REACTOME_DNA_REPAIR	0	8.18
Category members	GO Category	GO:0006511	ubiquitin-dependent protein catabolic process	Database	3.57
Category members	GO Category	GO:0004843	ubiquitin-specific protease activity	Database	3.28
Category members	GO Category	GO:0004221	ubiquitin thiolesterase activity	Database	1.36
Category members	GO Category	GO:0016579	protein deubiquitination	Database	1.32
Category members	Pathway	Pathway_873	PID_FANCONI_PATHWAY	0	1.09
Category members	GO Category	GO:0009411	response to UV	Database	0.79
Category members	GO Category	GO:0035520	monoubiquitinated protein deubiquitination	Database	0.54
Category members	Pathway	Pathway_829	REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY	0	0.38
Category members	GO Category	GO:0004197	cysteine-type endopeptidase activity	Database	0.38
Category members	Pathway	Pathway_812	REACTOME_FANCONI_ANEMIA_PATHWAY	0	0.29
Category members	GO Category	GO:0006282	regulation of DNA repair	Database	0