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Query: SNX2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNX2 0 2.487 -0.850 -0.050 -0.347 0.878

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SNX2 Ubiquitylation K181 0.631 1.039 _SEFSVK(gl)R_
SNX2 Phosphorylation S119 0.336 _SMS(ph)APVIFDR_
SNX2 Ubiquitylation K116 0.089 0.156 _IESK(gl)SMSAPVIFDR_
SNX2 Ubiquitylation K218 -0.014 _SIVGMTK(gl)VK_
SNX2 Ubiquitylation K220 -0.305 _VK(gl)VGKEDSSSTEFVEK_
SNX2 Ubiquitylation K294 -0.176 _AADAVNK(gl)MTIK_

Background Information for SNX2:


Pubmed-SNX2 »
Uniprot-SNX2 »
Biogrid-SNX2 »
ProteomicsDB-SNX2 »

Tumorportal-SNX2 »
COSMIC-SNX2 »
GenomeRNAi-SNX2 »
Genecards-SNX2


Protein-protein Interactions for SNX2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C11orf42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf87 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C7orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYB5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HENMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTEX1D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TREML2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNX2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phox IPR001683 0.24
Category members Vps5_C IPR015404 0.08
Category members Sorting_nexin_N IPR005329 0


Protein complexes (CORUM database) featuring SNX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1091 SNX complex (SNX1a, SNX2, SNX4, LEPR) Database 0.05
Category members Corum 1093 SNX complex (SNX1a, SNX2, SNX4, INSR) Database 0.05
Category members Corum 1095 SNX complex (SNX1a, SNX2, SNX4, EGFR) Database 0.05
Category members Corum 1096 SNX complex (SNX1,1a,2,4, PDGF receptor) Database 0.05
Category members Corum 1059 Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) Database 0
Category members Corum 1060 Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) Database 0
Category members Corum 1070 SNX complex (SNX1a, SNX2, SNX4) Database 0
Category members Corum 1104 SNX complex (SNX1a, SNX2, SNX4, TFRC) Database 0
Category members Corum 657 Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) Database 0


Categories featuring SNX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members GO Category GO:0007154 cell communication Database 0
Category members GO Category GO:0010008 endosome membrane Database 0


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