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Query: SH3BP4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SH3BP4 0 1.565 -0.080 0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SH3BP4 Phosphorylation S246 0.304 0.661 _SYS(ph)LSELSVLQAK_
SH3BP4 Phosphorylation S131 -0.309 _NSTLSDSGMIDNLPDS(ph)PDEVAK_

Background Information for SH3BP4:


Pubmed-SH3BP4 »
Uniprot-SH3BP4 »
Biogrid-SH3BP4 »
ProteomicsDB-SH3BP4 »

Tumorportal-SH3BP4 »
COSMIC-SH3BP4 »
GenomeRNAi-SH3BP4 »
Genecards-SH3BP4


Protein-protein Interactions for SH3BP4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait CETN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GIPC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTRK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOR1AIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SH3BP4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members ZU5_dom IPR000906 0
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring SH3BP4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SH3BP4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0017016 Ras GTPase binding Database 1.28
Category members GO Category GO:0032007 negative regulation of TOR signaling Database 0.33
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0005905 coated pit Database 0.17
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0005092 GDP-dissociation inhibitor activity Database 0
Category members GO Category GO:0010508 positive regulation of autophagy Database 0
Category members GO Category GO:0034260 negative regulation of GTPase activity Database 0
Category members GO Category GO:0050790 regulation of catalytic activity Database 0
Category members GO Category GO:0061462 protein localization to lysosome Database 0
Category members GO Category GO:0071230 cellular response to amino acid stimulus Database 0


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