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Query: RNASEL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNASEL 1 6.549 -0.830 1.400 1.079 -0.385 0.549 0.456

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNASEL Ubiquitylation K2061 0.441 0.872 _GLGNLK(gl)ILK_
RNASEL Ubiquitylation K106 0.667 _IAELLCK(gl)NDVTDGR_
RNASEL Ubiquitylation K1220 0.641 _GIGNVK(gl)ILR_
RNASEL Phosphorylation Y2666 0.598 _NRPDY(ph)VSEEEEDDEDFETAVKK_
RNASEL Phosphorylation T2293 0.717 0.584 _LNQSGTSVGT(ph)DEESDVTQEEER_
RNASEL Phosphorylation S796 0.553 0.575 _SYKYS(ph)PK_
RNASEL Phosphorylation S2668 0.584 0.573 _NRPDYVS(ph)EEEEDDEDFETAVK_
RNASEL Phosphorylation S3207 0.368 0.527 _IESFGS(ph)PK_
RNASEL Phosphorylation S1456 0.018 0.508 _SGSSFVHQAS(ph)FK_
RNASEL Phosphorylation S1573 0.499 _CVACQNPDKPS(ph)PSTSVPAPASFK_
RNASEL Phosphorylation S2805 -0.018 0.448 _SISS(ph)PSVSSETMDKPVDLSTR_
RNASEL Phosphorylation S2454 0.335 0.393 _DSLIT(ph)PHVS(ph)R_
RNASEL Ubiquitylation K2379 -0.664 0.332 _DQVLK(gl)LCANHR_
RNASEL Ubiquitylation K2358 0.436 0.327 _GIGDIK(gl)ILQNYDNK_
RNASEL Ubiquitylation K2396 -0.954 0.190 _ITPDMTLQNMK(gl)GTER_
RNASEL Phosphorylation S2280 0.065 0.135 _SALSPSKS(ph)PAK_
RNASEL Phosphorylation S2510 -0.171 0.107 _AVVS(ph)PPKFVFGSESVK_
RNASEL Phosphorylation S1400 -0.440 0.082 _ELVGPPLAETVFT(ph)PKTS(ph)PENVQDR_
RNASEL Phosphorylation S955 -0.786 0.030 _FESPATGILS(ph)PR_
RNASEL Phosphorylation S2276 0.074 0.029 _SALS(ph)PSKSPAK_
RNASEL Ubiquitylation K2935 -1.498 0.007 _SGEEDEEILFK(gl)ER_
RNASEL Phosphorylation S788 0.362 -0.041 _YSLS(ph)PSK_
RNASEL Phosphorylation S21 0.047 -0.107 _YIASVQGSTPS(ph)PR_
RNASEL Ubiquitylation K2592 -0.298 _NSDIEQSSDSK(gl)VK_
RNASEL Ubiquitylation K2594 -0.298 _NSDIEQSSDSK(gl)VK_
RNASEL Phosphorylation T1396 -0.510 -0.398 _ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR_
RNASEL Phosphorylation S2900 -0.395 -0.513 _VGEDEDGS(ph)DEEVVHNEDIHFEPIVSLPEVEVK_
RNASEL Ubiquitylation K776 -0.046 -0.521 _NADSEIK(gl)HSTPSPTR_
RNASEL Ubiquitylation K94 -0.527 _SVELNPTQK(gl)DLVLK_
RNASEL Phosphorylation S2250 1.539 -0.701 _EDALDDSVSSSSVHASPLAS(ph)SPVRK_
RNASEL Phosphorylation T2613 -0.775 -0.709 _NLFASFPTEESSINYTFKT(ph)PEK_
RNASEL Ubiquitylation K1963 -0.768 _STSGEGFQFGK(gl)K_
RNASEL Ubiquitylation K1964 -0.768 _STSGEGFQFGK(gl)K_
RNASEL Phosphorylation S1160 -1.328 _NHETDGGS(ph)AHGDDDDDGPHFEPVVPLPDKIEVK_
RNASEL Phosphorylation T1399 -0.665 _ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR_
RNASEL Phosphorylation S2251 -0.023 _EDALDDSVSSSSVHASPLASS(ph)PVRK_
RNASEL Ubiquitylation K2650 0.439 _ALATK(gl)LK_
RNASEL Phosphorylation S2804 0.874 _SIS(ph)SPSVSSETM(ox)DKPVDLSTR_

Background Information for RNASEL:


Pubmed-RNASEL »
Uniprot-RNASEL »
Biogrid-RNASEL »
ProteomicsDB-RNASEL »

Tumorportal-RNASEL »
COSMIC-RNASEL »
GenomeRNAi-RNASEL »
Genecards-RNASEL


Protein-protein Interactions for RNASEL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC37A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RNASEL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KEN_dom IPR010513 0.04
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ankyrin_rpt IPR002110 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members PUG-dom IPR006567 0
Category members LipoPS_kinase IPR010440 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring RNASEL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNASEL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019843 rRNA binding Database 0.46
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members Disease phenotype Familial_prostate_cancer Familial prostate cancer Database 0.07
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_913 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 0 0
Category members Disease phenotype PROSTATE_CANCER PROSTATE CANCER Database 0
Category members GO Category GO:0004521 endoribonuclease activity Database 0
Category members GO Category GO:0004540 ribonuclease activity Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0045071 negative regulation of viral genome replication Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0060337 type I interferon signaling pathway Database 0


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