RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
AGO2	1	0.370	-0.620		0.303	-0.277	-0.950	0.328
RNASEL	1	-0.830	1.400	1.079	-0.385		0.549	0.456
APEX1	0	0.630	-0.180				-0.057	-0.077
DROSHA	0	-0.480	0.490				-0.227	-0.962
CPSF3	0	0.760	-0.720	-0.001	-0.206	0.455	-0.433	0.066

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AGO2	Ubiquitylation	K381		0.665	_SAPDRQEEISK(gl)LMR_
AGO2	Phosphorylation	S387		-0.656	_SAS(ph)FNTDPYVR_
AGO2	Ubiquitylation	K550	0.445	1.991	_VGDTVLGMATQCVQMK(gl)NVQR_
AGO2	Ubiquitylation	K720	-1.047	0.670	_LFCTDK(gl)NER_
AGO2	Ubiquitylation	K726	0.458	0.936	_VGK(gl)SGNIPAGTTVDTK_
APEX1	Ubiquitylation	K25	-0.227		_GAVAEDGDELRTEPEAKK(gl)_
APEX1	Ubiquitylation	K58	-0.215		_TSPSGK(gl)PATLK_
CPSF3	Ubiquitylation	K348	0.384		_ELFESWCTDK(gl)R_
CPSF3	Ubiquitylation	K428	0.656	0.535	_LK(gl)AALIR_
CPSF3	Ubiquitylation	K465	0.422		_NTEAVTLNFRGEKLAK(gl)_
CPSF3	Ubiquitylation	K474	-0.536		_VMGFLADKK(gl)PEQGQR_
CPSF3	Ubiquitylation	K487	0.072	0.155	_VSGILVK(gl)R_
CPSF3	Ubiquitylation	K604	-0.159		_K(gl)LEMHVYSK_
DROSHA	Ubiquitylation	K1341	0.133		_YNFPQM(ox)AHQK(gl)R_
RNASEL	Phosphorylation	S21	0.047	-0.107	_YIASVQGSTPS(ph)PR_
RNASEL	Ubiquitylation	K94		-0.527	_SVELNPTQK(gl)DLVLK_
RNASEL	Ubiquitylation	K106		0.667	_IAELLCK(gl)NDVTDGR_
RNASEL	Ubiquitylation	K776	-0.046	-0.521	_NADSEIK(gl)HSTPSPTR_
RNASEL	Phosphorylation	S788	0.362	-0.041	_YSLS(ph)PSK_
RNASEL	Phosphorylation	S796	0.553	0.575	_SYKYS(ph)PK_
RNASEL	Phosphorylation	S955	-0.786	0.030	_FESPATGILS(ph)PR_
RNASEL	Phosphorylation	S1160		-1.328	_NHETDGGS(ph)AHGDDDDDGPHFEPVVPLPDKIEVK_
RNASEL	Ubiquitylation	K1220		0.641	_GIGNVK(gl)ILR_
RNASEL	Phosphorylation	T1396	-0.510	-0.398	_ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR_
RNASEL	Phosphorylation	T1399	-0.665		_ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR_
RNASEL	Phosphorylation	S1400	-0.440	0.082	_ELVGPPLAETVFT(ph)PKTS(ph)PENVQDR_
RNASEL	Phosphorylation	S1456	0.018	0.508	_SGSSFVHQAS(ph)FK_
RNASEL	Phosphorylation	S1573		0.499	_CVACQNPDKPS(ph)PSTSVPAPASFK_
RNASEL	Ubiquitylation	K1963		-0.768	_STSGEGFQFGK(gl)K_
RNASEL	Ubiquitylation	K1964		-0.768	_STSGEGFQFGK(gl)K_
RNASEL	Ubiquitylation	K2061	0.441	0.872	_GLGNLK(gl)ILK_
RNASEL	Phosphorylation	S2250	1.539	-0.701	_EDALDDSVSSSSVHASPLAS(ph)SPVRK_
RNASEL	Phosphorylation	S2251	-0.023		_EDALDDSVSSSSVHASPLASS(ph)PVRK_
RNASEL	Phosphorylation	S2276	0.074	0.029	_SALS(ph)PSKSPAK_
RNASEL	Phosphorylation	S2280	0.065	0.135	_SALSPSKS(ph)PAK_
RNASEL	Phosphorylation	T2293	0.717	0.584	_LNQSGTSVGT(ph)DEESDVTQEEER_
RNASEL	Ubiquitylation	K2358	0.436	0.327	_GIGDIK(gl)ILQNYDNK_
RNASEL	Ubiquitylation	K2379	-0.664	0.332	_DQVLK(gl)LCANHR_
RNASEL	Ubiquitylation	K2396	-0.954	0.190	_ITPDMTLQNMK(gl)GTER_
RNASEL	Phosphorylation	S2454	0.335	0.393	_DSLIT(ph)PHVS(ph)R_
RNASEL	Phosphorylation	S2510	-0.171	0.107	_AVVS(ph)PPKFVFGSESVK_
RNASEL	Ubiquitylation	K2592		-0.298	_NSDIEQSSDSK(gl)VK_
RNASEL	Ubiquitylation	K2594		-0.298	_NSDIEQSSDSK(gl)VK_
RNASEL	Phosphorylation	T2613	-0.775	-0.709	_NLFASFPTEESSINYTFKT(ph)PEK_
RNASEL	Ubiquitylation	K2650	0.439		_ALATK(gl)LK_
RNASEL	Phosphorylation	Y2666		0.598	_NRPDY(ph)VSEEEEDDEDFETAVKK_
RNASEL	Phosphorylation	S2668	0.584	0.573	_NRPDYVS(ph)EEEEDDEDFETAVK_
RNASEL	Phosphorylation	S2804	0.874		_SIS(ph)SPSVSSETM(ox)DKPVDLSTR_
RNASEL	Phosphorylation	S2805	-0.018	0.448	_SISS(ph)PSVSSETMDKPVDLSTR_
RNASEL	Phosphorylation	S2900	-0.395	-0.513	_VGEDEDGS(ph)DEEVVHNEDIHFEPIVSLPEVEVK_
RNASEL	Ubiquitylation	K2935	-1.498	0.007	_SGEEDEEILFK(gl)ER_
RNASEL	Phosphorylation	S3207	0.368	0.527	_IESFGS(ph)PK_