bioLOGIC-db

bioLOGIC Data

Query: DROSHA

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
DROSHA	0	-0.566	-0.480	0.490				-0.227	-0.962

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
DROSHA	Ubiquitylation	K1341	0.133		_YNFPQM(ox)AHQK(gl)R_

ProteomicsDB-DROSHA »

Protein-protein Interactions for DROSHA

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait DGCR8	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait DYNC1LI1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait LNPEP	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NCK1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PSMB4	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RPA1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SGOL1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TRAPPC8	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ZNFX1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CHRNA9	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DGCR8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SRPK1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in DROSHA

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	dsRNA-bd_dom	IPR014720	0.23
Category members	RNase_III_dom	IPR000999	0

Protein complexes (CORUM database) featuring DROSHA

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	1332	Large Drosha complex	Database	0.08
Category members	Corum	3056	Microprocessor complex	Database	0
Category members	Corum	3081	Microprocessor complex	Database	0

Categories featuring DROSHA

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0003723	RNA binding	Database	INF
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005654	nucleoplasm	Database	INF
Category members	GO Category	GO:0010467	gene expression	Database	INF
Category members	GO Category	GO:0005730	nucleolus	Database	13.38
Category members	GO Category	GO:0016075	rRNA catabolic process	Database	0.48
Category members	GO Category	GO:0042254	ribosome biogenesis	Database	0.29
Category members	Pathway	Pathway_383	PID_P53_DOWNSTREAM_PATHWAY	0	0.23
Category members	Pathway	Pathway_368	REACTOME_MICRORNA_MIRNA_BIOGENESIS	0	0.18
Category members	GO Category	GO:0006396	RNA processing	Database	0.17
Category members	Pathway	Pathway_379	REACTOME_REGULATORY_RNA_PATHWAYS	0	0.12
Category members	GO Category	GO:0010586	miRNA metabolic process	Database	0.05
Category members	GO Category	GO:0031054	pre-miRNA processing	Database	0.01
Category members	GO Category	GO:0004521	endoribonuclease activity	Database	0
Category members	GO Category	GO:0004525	ribonuclease III activity	Database	0
Category members	GO Category	GO:0010468	regulation of gene expression	Database	0
Category members	GO Category	GO:0046872	metal ion binding	Database	0