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Query: QKI

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
QKI 0 -3.392 1.130 -0.950 -2.091 -0.975
QKI 0 -3.392 1.130 -0.950 -1.223

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
QKI Ubiquitylation K111 0.236 0.638 _GLTAK(gl)QLEAETGCK_
QKI Ubiquitylation K91 -0.019 -0.167 _LYVPVK(gl)EYPDFNFVGR_
QKI Ubiquitylation K190 -0.178 _LLVPAAEGEDSLK(gl)K_
QKI Ubiquitylation K191 0.259 -0.178 _LLVPAAEGEDSLKK(gl)_

Background Information for QKI:


Pubmed-QKI »
Uniprot-QKI »
Biogrid-QKI »
ProteomicsDB-QKI »

Tumorportal-QKI »
COSMIC-QKI »
GenomeRNAi-QKI »
Genecards-QKI


Protein-protein Interactions for QKI
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXW11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRPLL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QKI Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAC14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in QKI
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring QKI
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring QKI
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0042552 myelination Database 0.16
Category members GO Category GO:0042692 muscle cell differentiation Database 0.1
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0008366 axon ensheathment Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0042759 long-chain fatty acid biosynthetic process Database 0


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