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Query: PTPRU

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTPRU 0 -0.235 0.620 0.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTPRU Phosphorylation S853 -0.196 -0.039 _SGGVTEASSLLGGS(ph)PR_

Background Information for PTPRU:


Pubmed-PTPRU »
Uniprot-PTPRU »
Biogrid-PTPRU »
ProteomicsDB-PTPRU »

Tumorportal-PTPRU »
COSMIC-PTPRU »
GenomeRNAi-PTPRU »
Genecards-PTPRU


Protein-protein Interactions for PTPRU
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AAMP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PTPRU
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Fibronectin_type3 IPR003961 0.19
Category members Tyr_Pase_rcpt/non-rcpt IPR000242 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members MAM_dom IPR000998 0
Category members Tyr_Pase_cat IPR003595 0
Category members ConA-like_lec_gl_sf IPR008985 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring PTPRU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PTPRU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members GO Category GO:0031100 organ regeneration Database 0.01
Category members Pathway Pathway_1179 ST_STAT3_PATHWAY 0 0
Category members Pathway Pathway_1225 ST_TYPE_I_INTERFERON_PATHWAY 0 0
Category members Pathway Pathway_166 ST_JAK_STAT_PATHWAY 0 0
Category members Pathway Pathway_719 ST_INTERFERON_GAMMA_PATHWAY 0 0
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0005001 transmembrane receptor protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0034109 homotypic cell-cell adhesion Database 0
Category members GO Category GO:0034394 protein localization to cell surface Database 0
Category members GO Category GO:0035335 peptidyl-tyrosine dephosphorylation Database 0
Category members GO Category GO:0060070 canonical Wnt signaling pathway Database 0


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