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Query: OFD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OFD1 0 0.131 1.920 -1.210 -0.269

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OFD1 Ubiquitylation K218 0.010 _AEMCQK(gl)LK_
OFD1 Phosphorylation S899 -0.092 _RQS(ph)NLQEVLER_
OFD1 Phosphorylation S774 -0.145 -0.111 _MPLPS(ph)PTESR_
OFD1 Phosphorylation S788 -0.298 _HSLSIPPVS(ph)SPPEQK_
OFD1 Phosphorylation S735 0.482 -0.458 _RLS(ph)STPLPK_
OFD1 Ubiquitylation K256 -0.642 _ACQAK(gl)SEALVLR_
OFD1 Phosphorylation S669 -0.349 -0.888 _S(ph)PPSLHLLEAFK_
OFD1 Phosphorylation S789 -0.909 _HSLSIPPVSS(ph)PPEQK_
OFD1 Ubiquitylation K533 -0.930 _ASVK(gl)SLTTQVADLK_
OFD1 Phosphorylation S762 -0.735 -0.990 _SHIAS(ph)PSPCPDR_

Background Information for OFD1:


Pubmed-OFD1 »
Uniprot-OFD1 »
Biogrid-OFD1 »
ProteomicsDB-OFD1 »

Tumorportal-OFD1 »
COSMIC-OFD1 »
GenomeRNAi-OFD1 »
Genecards-OFD1


Protein-protein Interactions for OFD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD26 Cat. description Hein, Mann, Cell 2015
Category members IP bait AZI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C14ORF10;PPP2R3C Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC77 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCP110 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP120 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP290 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait COBLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1E Cat. description Hein, Mann, Cell 2015
Category members IP bait DLG5 Cat. description Hein, Mann, Cell 2015
Category members IP bait DNAJC7 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait HSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRRCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait OFD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNT Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2B Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENSA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIS18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDEL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OFD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members LisH_dimerisation IPR006594 0.06


Protein complexes (CORUM database) featuring OFD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OFD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0006952 defense response Database 0.32
Category members Disease phenotype Joubert_syndrome_with_orofaciodigital_defect Joubert syndrome with orofaciodigital defect Database 0
Category members Disease phenotype Primary_ciliary_dyskinesia Primary ciliary dyskinesia Database 0
Category members Disease phenotype Retinitis_pigmentosa Retinitis pigmentosa Database 0
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0009279 cell outer membrane Database 0
Category members GO Category GO:0034451 centriolar satellite Database 0
Category members GO Category GO:0043014 alpha-tubulin binding Database 0
Category members GO Category GO:0043015 gamma-tubulin binding Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0
Category members GO Category GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry Database 0


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