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Query: NR2F2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NR2F2 0 1.927 -1.120 1.260 0.225 0.992 0.424 0.474
NR2F2 0 1.927 -1.120 1.260 -1.119 0.136 0.670

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NR2F2 Ubiquitylation K362 0.144 _FGK(gl)LLLR_
NR2F2 Ubiquitylation K389 -0.473 -0.156 _LVGK(gl)TPIETLIR_

Background Information for NR2F2:


Pubmed-NR2F2 »
Uniprot-NR2F2 »
Biogrid-NR2F2 »
ProteomicsDB-NR2F2 »

Tumorportal-NR2F2 »
COSMIC-NR2F2 »
GenomeRNAi-NR2F2 »
Genecards-NR2F2


Protein-protein Interactions for NR2F2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AIFM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERGIC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM126A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCGR3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR77 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SALL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC18A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC37A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPPL2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TM2D3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NR2F2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members COUP_TF IPR003068 0.18
Category members Retinoid-X_rcpt/HNF4 IPR000003 0
Category members Nucl_hrmn_rcpt_lig-bd_core IPR000536 0
Category members Znf_hrmn_rcpt IPR001628 0
Category members Str_hrmn_rcpt IPR001723 0
Category members ThyrH_rcpt IPR001728 0
Category members Nucl_hormone_rcpt_ligand-bd IPR008946 0


Protein complexes (CORUM database) featuring NR2F2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NR2F2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0030522 intracellular receptor signaling pathway Database 0.9
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0010596 negative regulation of endothelial cell migration Database 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_186 PID_HNF3A_PATHWAY 0 0
Category members Disease phenotype Partial_atrioventricular_canal Partial atrioventricular canal Database 0
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0001893 maternal placenta development Database 0
Category members GO Category GO:0001937 negative regulation of endothelial cell proliferation Database 0
Category members GO Category GO:0001945 lymph vessel development Database 0
Category members GO Category GO:0001972 retinoic acid binding Database 0
Category members GO Category GO:0003707 steroid hormone receptor activity Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007519 skeletal muscle tissue development Database 0
Category members GO Category GO:0009566 fertilization Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043401 steroid hormone mediated signaling pathway Database 0
Category members GO Category GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity Database 0
Category members GO Category GO:0048514 blood vessel morphogenesis Database 0
Category members GO Category GO:0060173 limb development Database 0
Category members GO Category GO:0060674 placenta blood vessel development Database 0
Category members GO Category GO:0060707 trophoblast giant cell differentiation Database 0
Category members GO Category GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment Database 0


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