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Query: NISCH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NISCH 0 1.035 0.060 0.270 -0.247 0.240

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NISCH Ubiquitylation K942 0.996 _NSFK(gl)LSR_
NISCH Ubiquitylation K1303 0.675 0.227 _TTGK(gl)MENYELIHSSR_
NISCH Phosphorylation S1284 -0.365 -0.534 _TPS(ph)PEPVDKDFYSEFGNK_
NISCH Ubiquitylation K1009 0.484 _ASLQDLK(gl)TVVIAK_

Background Information for NISCH:


Pubmed-NISCH »
Uniprot-NISCH »
Biogrid-NISCH »
ProteomicsDB-NISCH »

Tumorportal-NISCH »
COSMIC-NISCH »
GenomeRNAi-NISCH »
Genecards-NISCH


Protein-protein Interactions for NISCH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CNKSR3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1G2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAVCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ODAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIK3R3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UNC119 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NISCH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt IPR001611 0.32
Category members Phox IPR001683 0.24


Protein complexes (CORUM database) featuring NISCH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NISCH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0032228 regulation of synaptic transmission, GABAergic Database 0.19
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0008217 regulation of blood pressure Database 0.09
Category members GO Category GO:0007154 cell communication Database 0
Category members GO Category GO:0008227 G-protein coupled amine receptor activity Database 0
Category members GO Category GO:0016601 Rac protein signal transduction Database 0


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