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Query: NDUFA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NDUFA1 0 -2.154 -0.970 0.750

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NDUFA1 Ubiquitylation K64 -2.721 -0.183 _YYVSK(gl)GLENID_

Background Information for NDUFA1:


Pubmed-NDUFA1 »
Uniprot-NDUFA1 »
Biogrid-NDUFA1 »
ProteomicsDB-NDUFA1 »

Tumorportal-NDUFA1 »
COSMIC-NDUFA1 »
GenomeRNAi-NDUFA1 »
Genecards-NDUFA1


Protein-protein Interactions for NDUFA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NDUFA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOR1AIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NDUFA1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring NDUFA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2939 Ecsit complex (ECSIT, MT-CO2, NDUFA1, MT-ND1, TRAF6, NDUFAF1) Database 0.09


Categories featuring NDUFA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members Disease phenotype Mitochondrial_Respiratory_Chain_Complex_I_Deficiency_(nuclear_genes) Mitochondrial Respiratory Chain Complex I Deficiency (nuclear genes) Database 0.6
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members Disease phenotype MITOCHONDRIAL_COMPLEX_I_DEFICIENCY MITOCHONDRIAL COMPLEX I DEFICIENCY Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Disease phenotype Isolated_NADH-CoQ_reductase_deficiency Isolated NADH-CoQ reductase deficiency Database 0.17
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0008137 NADH dehydrogenase (ubiquinone) activity Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members GO Category GO:0005747 mitochondrial respiratory chain complex I Database 0.08
Category members GO Category GO:0006120 mitochondrial electron transport, NADH to ubiquinone Database 0.07
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Pathway Pathway_48 BIOCARTA_ETC_PATHWAY 0 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0


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