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Query: IFI16

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IFI16 0 1.210 0.400 -0.680 0.620 0.590

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for IFI16:


Pubmed-IFI16 »
Uniprot-IFI16 »
Biogrid-IFI16 »
ProteomicsDB-IFI16 »

Tumorportal-IFI16 »
COSMIC-IFI16 »
GenomeRNAi-IFI16 »
Genecards-IFI16


Protein-protein Interactions for IFI16
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015


Protein Domains in IFI16
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DEATH-like_dom IPR011029 1.15
Category members DAPIN IPR004020 0.05
Category members HIN200/IF120x IPR004021 0


Protein complexes (CORUM database) featuring IFI16
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IFI16
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Database 0.83
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0030224 monocyte differentiation Database 0.45
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0032731 positive regulation of interleukin-1 beta production Database 0.08
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0001819 positive regulation of cytokine production Database 0.05
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0043392 negative regulation of DNA binding Database 0.01
Category members GO Category GO:0002218 activation of innate immune response Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0010506 regulation of autophagy Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0030099 myeloid cell differentiation Database 0
Category members GO Category GO:0042149 cellular response to glucose starvation Database 0
Category members GO Category GO:0045071 negative regulation of viral genome replication Database 0
Category members GO Category GO:0045824 negative regulation of innate immune response Database 0


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