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Query: HOXD13

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HOXD13 0 -0.426 1.230 -1.330 -0.993
HOXD13 0 -0.426 1.230 -1.330 -0.027 0.427

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HOXD13 Ubiquitylation K335 0.431 0.162 _VQLK(gl)ELER_

Background Information for HOXD13:


Pubmed-HOXD13 »
Uniprot-HOXD13 »
Biogrid-HOXD13 »
ProteomicsDB-HOXD13 »

Tumorportal-HOXD13 »
COSMIC-HOXD13 »
GenomeRNAi-HOXD13 »
Genecards-HOXD13


Protein-protein Interactions for HOXD13
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait F9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HOXD13
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members Homeodomain-like IPR009057 0
Category members HoxA13_N IPR022067 0


Protein complexes (CORUM database) featuring HOXD13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HOXD13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0007389 pattern specification process Database 0.18
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0022612 gland morphogenesis Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030539 male genitalia development Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0048619 embryonic hindgut morphogenesis Database 0
Category members GO Category GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Database 0
Category members GO Category GO:0060571 morphogenesis of an epithelial fold Database 0
Category members GO Category GO:0060687 regulation of branching involved in prostate gland morphogenesis Database 0


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