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Query: HOXA13

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HOXA13 1 3.645 -1.850 3.840 -0.027 0.427
HOXA13 1 3.645 -1.850 3.840 -1.413 0.651

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HOXA13 Ubiquitylation K335 0.431 0.162 _VQLK(gl)ELER_

Background Information for HOXA13:





Protein-protein Interactions for HOXA13

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HOXA13

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members Antifreeze_1 IPR000104 0.24
Category members Homeodomain-like IPR009057 0
Category members HoxA13_N IPR022067 0


Protein complexes (CORUM database) featuring HOXA13

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HOXA13

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0030510 regulation of BMP signaling pathway Database 0.09
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0001886 endothelial cell morphogenesis Database 0
Category members GO Category GO:0001894 tissue homeostasis Database 0
Category members GO Category GO:0003281 ventricular septum development Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0030539 male genitalia development Database 0
Category members GO Category GO:0035115 embryonic forelimb morphogenesis Database 0
Category members GO Category GO:0045840 positive regulation of mitosis Database 0
Category members GO Category GO:0048839 inner ear development Database 0
Category members GO Category GO:0048844 artery morphogenesis Database 0
Category members GO Category GO:0060442 branching involved in prostate gland morphogenesis Database 0


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