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Query: HDGF

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HDGF 0 1.337 -0.810 0.160

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HDGF Phosphorylation S181 0.232 0.201 _RAGDLLEDS(ph)PK_
HDGF Phosphorylation S148 0.175 0.116 _KGNAEGS(ph)SDEEGKLVIDEPAK_
HDGF Phosphorylation S149 0.156 -0.009 _GNAEGSS(ph)DEEGKLVIDEPAKEK_
HDGF Ubiquitylation K11 0.744 _EYK(gl)CGDLVFAK_
HDGF Ubiquitylation K39 0.518 _IDEMPEAAVK(gl)STANK_

Background Information for HDGF:


Pubmed-HDGF »
Uniprot-HDGF »
Biogrid-HDGF »
ProteomicsDB-HDGF »

Tumorportal-HDGF »
COSMIC-HDGF »
GenomeRNAi-HDGF »
Genecards-HDGF


Protein-protein Interactions for HDGF
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CPNE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EGFL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HDGF
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PWWP_dom IPR000313 0.63


Protein complexes (CORUM database) featuring HDGF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5615 Emerin complex 52 Database 0.99


Categories featuring HDGF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0008083 growth factor activity Database 2.34
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0008201 heparin binding Database 0.27
Category members GO Category GO:0034504 protein localization to nucleus Database 0.15
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0001106 RNA polymerase II transcription corepressor activity Database 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0001222 transcription corepressor binding Database 0
Category members GO Category GO:0007165 signal transduction Database 0


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