bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: FGFR1OP

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FGFR1OP 1 2.433 -0.600 0.800

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FGFR1OP Phosphorylation S326 1.712 _IGS(ph)LGLGTGEDDDYVDDFNSTSHR_
FGFR1OP Phosphorylation S160 -0.079 -0.321 _EKGPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK_
FGFR1OP Phosphorylation S156 -0.647 -0.663 _EKGPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK_
FGFR1OP Phosphorylation T170 -0.492 -1.069 _TSAQTT(ph)PSKIPR_

Background Information for FGFR1OP:


Pubmed-FGFR1OP »
Uniprot-FGFR1OP »
Biogrid-FGFR1OP »
ProteomicsDB-FGFR1OP »

Tumorportal-FGFR1OP »
COSMIC-FGFR1OP »
GenomeRNAi-FGFR1OP »
Genecards-FGFR1OP


Protein-protein Interactions for FGFR1OP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD26 Cat. description Hein, Mann, Cell 2015
Category members IP bait AZI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C14ORF10;PPP2R3C Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait LRRCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait OFD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait C4orf6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C7orf69 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP2CB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FGFR1OP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members LisH_dimerisation IPR006594 0.06
Category members FOP_dimerisation-dom_N IPR018993 0


Protein complexes (CORUM database) featuring FGFR1OP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FGFR1OP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_265 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 0 1.42
Category members Pathway Pathway_559 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS 0 1.1
Category members GO Category GO:0034453 microtubule anchoring Database 0.97
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_592 REACTOME_SIGNALING_BY_FGFR1_MUTANTS 0 0.4
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_528 REACTOME_SIGNALING_BY_FGFR_MUTANTS 0 0.37
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0030292 protein tyrosine kinase inhibitor activity Database 0.11
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0018108 peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0030307 positive regulation of cell growth Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0061099 negative regulation of protein tyrosine kinase activity Database 0


.

© Copyright Svejstrup Laboratory 2015