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negative regulation of protein tyrosine kinase activity
(GO:0061099)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GNB2L1 1 1.000 -0.100 0.279 1.704
GNB2L1 1 1.000 -0.100 -0.278 -0.107 -0.424
FGFR1OP 1 -0.600 0.800
IBTK 0 0.890 -0.470
IBTK 0 0.940 -0.610
PTK6 0 -0.300 0.700 0.520 0.139 1.329 0.365 0.320

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
FGFR1OP Phosphorylation S156 -0.647 -0.663 _EKGPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK_
FGFR1OP Phosphorylation S160 -0.079 -0.321 _EKGPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK_
FGFR1OP Phosphorylation T170 -0.492 -1.069 _TSAQTT(ph)PSKIPR_
FGFR1OP Phosphorylation S326 1.712 _IGS(ph)LGLGTGEDDDYVDDFNSTSHR_
GNB2L1 Ubiquitylation K38 -0.238 0.350 _DK(gl)TIIMWK_
GNB2L1 Ubiquitylation K106 -0.290 _RFVGHTK(gl)DVLSVAFSSDNR_
GNB2L1 Ubiquitylation K130 0.632 _TIK(gl)LWNTLGVCK_
GNB2L1 Ubiquitylation K175 -0.554 -0.015 _LVK(gl)VWNLANCK_
GNB2L1 Ubiquitylation K183 -0.161 -0.282 _VWNLANCK(gl)_
GNB2L1 Ubiquitylation K185 -0.061 -0.249 _VWNLANCKLK(gl)_
GNB2L1 Ubiquitylation K257 -0.288 _YWLCAATGPSIK(gl)_
GNB2L1 Ubiquitylation K271 0.756 -0.007 _IIVDELK(gl)QEVISTSSK_
IBTK Phosphorylation S992 0.164 _SDS(ph)SGGYNLSDIIQSPSS(ph)TGLLK_
IBTK Phosphorylation S1004 -0.363 0.249 _SDSSGGYNLSDIIQS(ph)PSSTGLLK_
IBTK Phosphorylation S1045 0.071 0.109 _DLQS(ph)PDFTTGFHSDK_
IBTK Phosphorylation S1083 -0.072 _EDLKPWEKS(ph)PILK_
PTK6 Phosphorylation S47 0.375 0.573 _RDS(ph)LEEGELR_
PTK6 Phosphorylation T61 0.721 _MEIT(ph)IRNSPYR_
PTK6 Phosphorylation S65 0.730 0.552 _MEITIRNS(ph)PYR_
PTK6 Phosphorylation S234 -0.737 -0.712 _S(ph)PPRPPR_
PTK6 Phosphorylation S283 0.324 0.483 _DLLSDLQDIS(ph)DSER_
PTK6 Ubiquitylation K467 -0.286 _TDEIVALK(gl)R_
PTK6 Phosphorylation S589 0.529 0.585 _EYGS(ph)PLKAYT(ph)PVVVTLWYR_
PTK6 Phosphorylation T595 0.472 0.397 _AYT(ph)PVVVTLWYR_
PTK6 Ubiquitylation K672 -1.465 _IWPGYSELPAVK(gl)K_
PTK6 Ubiquitylation K673 -1.465 _IWPGYSELPAVK(gl)K_
PTK6 Ubiquitylation K719 -0.672 _ISAEDGLK(gl)HEYFR_
PTK6 Phosphorylation T751 -0.349 -0.460 _RGT(ph)SPRPPEGGLGYSQLGDDDLK_
PTK6 Phosphorylation S752 -0.526 -0.643 _RGTS(ph)PRPPEGGLGYSQLGDDDLK_


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