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Query: IBTK

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IBTK 0 0.320 0.890 -0.470
IBTK 0 0.320 0.940 -0.610

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IBTK Phosphorylation S1004 -0.363 0.249 _SDSSGGYNLSDIIQS(ph)PSSTGLLK_
IBTK Phosphorylation S992 0.164 _SDS(ph)SGGYNLSDIIQSPSS(ph)TGLLK_
IBTK Phosphorylation S1045 0.071 0.109 _DLQS(ph)PDFTTGFHSDK_
IBTK Phosphorylation S1083 -0.072 _EDLKPWEKS(ph)PILK_

Background Information for IBTK:


Pubmed-IBTK »
Uniprot-IBTK »
Biogrid-IBTK »
ProteomicsDB-IBTK »

Tumorportal-IBTK »
COSMIC-IBTK »
GenomeRNAi-IBTK »
Genecards-IBTK


Protein-protein Interactions for IBTK
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLASP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DOT1L Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait EZR Cat. description Hein, Mann, Cell 2015
Category members IP bait FTSJ1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SARS Cat. description Hein, Mann, Cell 2015
Category members IP bait TTK Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IBTK
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members BTB/POZ-like IPR000210 0.43
Category members BTB/POZ_fold IPR011333 0.36
Category members BTB_POZ IPR013069 0.32
Category members RCC1/BLIP-II IPR009091 0.24
Category members Reg_chr_condens IPR000408 0.23
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring IBTK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IBTK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0030292 protein tyrosine kinase inhibitor activity Database 0.11
Category members GO Category GO:0001933 negative regulation of protein phosphorylation Database 0.04
Category members GO Category GO:0051209 release of sequestered calcium ion into cytosol Database 0.01
Category members Pathway Pathway_540 PID_BCR_5PATHWAY 0 0
Category members GO Category GO:0061099 negative regulation of protein tyrosine kinase activity Database 0


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