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Query: CTSD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTSD 0 -3.404 0.580 -0.790 -0.768 -2.790 -0.655 -1.981

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CTSD:


Pubmed-CTSD »
Uniprot-CTSD »
Biogrid-CTSD »
ProteomicsDB-CTSD »

Tumorportal-CTSD »
COSMIC-CTSD »
GenomeRNAi-CTSD »
Genecards-CTSD


Protein-protein Interactions for CTSD
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait NAPSA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTSD
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aspartic_peptidase IPR001461 0
Category members Aspartic_peptidase_N IPR012848 0
Category members Peptidase_aspartic_dom IPR021109 0


Protein complexes (CORUM database) featuring CTSD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CTSD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members Pathway Pathway_54 BIOCARTA_MTA3_PATHWAY 0 0.36
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0030574 collagen catabolic process Database 0.2
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0022617 extracellular matrix disassembly Database 0.13
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0043202 lysosomal lumen Database 0.07
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members Pathway Pathway_734 PID_CERAMIDE_PATHWAY 0 0
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0000045 autophagic vacuole assembly Database 0
Category members GO Category GO:0004190 aspartic-type endopeptidase activity Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006508 proteolysis Database 0


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