Results for the Category
aspartic-type endopeptidase activity
(GO:0004190)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PSEN2 | 1 | -1.820 | 3.280 | |||||
| PSEN1 | 0 | 0.930 | -1.110 | |||||
| HM13 | 0 | -0.640 | 0.080 | -0.261 | 0.099 | |||
| EDEM3 | 0 | -0.320 | 0.890 | |||||
| CTSD | 0 | 0.580 | -0.790 | -0.768 | -2.790 | -0.655 | -1.981 | |
| CASP3 | 0 | 0.570 | -0.390 | |||||
| CASP7 | 0 | 0.130 | -0.130 | |||||
| ATP6AP2 | 0 | -0.880 | 1.100 | -0.462 | -0.359 | |||
| DDI2 | 0 | 0.246 | ||||||
| ASPRV1 | 0 | -0.850 | 1.970 | -5.193 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ATP6AP2 | Ubiquitylation | K284 | 0.459 | _TILEAK(gl)QAK_ | |
| ATP6AP2 | Ubiquitylation | K346 | -0.181 | _MTNQK(gl)IR_ | |
| CASP3 | Ubiquitylation | K11 | -0.053 | -0.687 | _(ac)MENTENSVDSK(gl)SIK_ |
| CASP3 | Ubiquitylation | K14 | -0.455 | -0.687 | _SIK(gl)NLEPK_ |
| CASP3 | Ubiquitylation | K57 | -0.304 | -1.817 | _NFHK(gl)STGMTSR_ |
| CASP3 | Ubiquitylation | K82 | -0.268 | -0.605 | _NLK(gl)YEVR_ |
| CASP7 | Phosphorylation | S16 | 0.096 | -0.112 | _(ac)ADDQGCIEEQGVEDS(ph)ANEDSVDAKPDR_ |
| CASP7 | Ubiquitylation | K80 | 0.580 | -0.044 | _NFDK(gl)VTGMGVR_ |
| DDI2 | Ubiquitylation | K67 | -0.155 | 0.530 | _SLASYGLK(gl)DGDVVILR_ |
| DDI2 | Ubiquitylation | K77 | -1.935 | _QK(gl)ENADPRPPVQFPNLPR_ | |
| DDI2 | Phosphorylation | T104 | -0.261 | _IDFSSIAVPGT(ph)SSPR_ | |
| DDI2 | Phosphorylation | S105 | -0.813 | -0.442 | _IDFSSIAVPGTS(ph)SPR_ |
| DDI2 | Phosphorylation | S106 | -0.202 | -0.329 | _IDFSSIAVPGTSS(ph)PR_ |
| DDI2 | Phosphorylation | S121 | -0.908 | _QRQPPGTQQSHSS(ph)PGEITSSPQGLDNPALLR_ | |
| DDI2 | Ubiquitylation | K153 | -0.208 | 0.772 | _DMLLANPHELSLLK(gl)ER_ |
| DDI2 | Ubiquitylation | K170 | -1.551 | _NPPLAEALLSGDLEK(gl)FSR_ | |
| DDI2 | Ubiquitylation | K283 | -0.091 | 0.951 | _WAGIAK(gl)GVGTQK_ |
| DDI2 | Ubiquitylation | K289 | -0.258 | 0.868 | _GVGTQK(gl)IIGR_ |
| EDEM3 | Ubiquitylation | K435 | -1.055 | _TLIENLNK(gl)YAR_ | |
| EDEM3 | Ubiquitylation | K447 | 0.123 | _VPCGFAAMK(gl)DVR_ | |
| HM13 | Ubiquitylation | K61 | -0.651 | 0.407 | _GK(gl)NASDMPETITSR_ |
| HM13 | Ubiquitylation | K241 | 1.147 | _SFEAPIK(gl)LVFPQDLLEK_ | |
| HM13 | Ubiquitylation | K285 | 1.086 | _FDISLKK(gl)_ | |
| HM13 | Ubiquitylation | K370 | -0.544 | 0.500 | _EGTEASASK(gl)GLEK_ |
| PSEN1 | Phosphorylation | S313 | 0.844 | _VSKNS(ph)KYNAESTER_ | |
| PSEN1 | Ubiquitylation | K314 | 0.016 | 0.414 | _NSK(gl)YNAESTER_ |
| PSEN1 | Phosphorylation | S366 | -0.340 | 0.055 | _AAVQELSS(ph)SILAGEDPEER_ |
| PSEN1 | Phosphorylation | S367 | 0.005 | 0.066 | _AAVQELSSS(ph)ILAGEDPEER_ |
| PSEN2 | Phosphorylation | S58 | -0.112 | -0.130 | _TSLM(ox)SAES(ph)PTPR_ |
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© Copyright Svejstrup Laboratory 2015