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Query: HM13

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HM13 0 0.520 -0.640 0.080 -0.261 0.099

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HM13 Ubiquitylation K241 1.147 _SFEAPIK(gl)LVFPQDLLEK_
HM13 Ubiquitylation K285 1.086 _FDISLKK(gl)_
HM13 Ubiquitylation K370 -0.544 0.500 _EGTEASASK(gl)GLEK_
HM13 Ubiquitylation K61 -0.651 0.407 _GK(gl)NASDMPETITSR_

Background Information for HM13:


Pubmed-HM13 »
Uniprot-HM13 »
Biogrid-HM13 »
ProteomicsDB-HM13 »

Tumorportal-HM13 »
COSMIC-HM13 »
GenomeRNAi-HM13 »
Genecards-HM13


Protein-protein Interactions for HM13
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SEL1L Cat. description Hein, Mann, Cell 2015
Category members IP bait C15orf27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HM13
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Preselin/SPP IPR006639 0
Category members Peptidase_A22B_SPP IPR007369 0


Protein complexes (CORUM database) featuring HM13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HM13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members GO Category GO:0004190 aspartic-type endopeptidase activity Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0033619 membrane protein proteolysis Database 0
Category members GO Category GO:0042500 aspartic endopeptidase activity, intramembrane cleaving Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0071458 integral to cytosolic side of endoplasmic reticulum membrane Database 0


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