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Query: CDH2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDH2 0 -2.070 -0.110 -0.060 -1.092 -0.918

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CDH2:


Pubmed-CDH2 »
Uniprot-CDH2 »
Biogrid-CDH2 »
ProteomicsDB-CDH2 »

Tumorportal-CDH2 »
COSMIC-CDH2 »
GenomeRNAi-CDH2 »
Genecards-CDH2


Protein-protein Interactions for CDH2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CTNNA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDH2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cadherin/Desmocollin IPR009124 1.19
Category members Cadherin_pro_dom IPR014868 0.78
Category members Cadherin IPR002126 0.32
Category members Cadherin_cytoplasmic-dom IPR000233 0.29
Category members Cadherin-like IPR015919 0.21
Category members PH_domain IPR001849 0.14


Protein complexes (CORUM database) featuring CDH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members GO Category GO:0051146 striated muscle cell differentiation Database 1.01
Category members GO Category GO:0014704 intercalated disc Database 0.64
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005916 fascia adherens Database 0.47
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0019903 protein phosphatase binding Database 0.33
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members GO Category GO:0007156 homophilic cell adhesion Database 0.28
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0045295 gamma-catenin binding Database 0.23
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0045216 cell-cell junction organization Database 0.1
Category members GO Category GO:0042692 muscle cell differentiation Database 0.1
Category members GO Category GO:0043410 positive regulation of MAPK cascade Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0007157 heterophilic cell-cell adhesion Database 0.04
Category members GO Category GO:0051149 positive regulation of muscle cell differentiation Database 0.04
Category members Pathway Pathway_1007 KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 0 0.03
Category members GO Category GO:0045294 alpha-catenin binding Database 0.03
Category members Pathway Pathway_1038 REACTOME_MYOGENESIS 0 0
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_1237 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION 0 0
Category members Pathway Pathway_1276 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS 0 0
Category members Pathway Pathway_602 PID_PTP1B_PATHWAY 0 0
Category members Pathway Pathway_657 PID_FGF_PATHWAY 0 0
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0016339 calcium-dependent cell-cell adhesion Database 0
Category members GO Category GO:0016342 catenin complex Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0034332 adherens junction organization Database 0
Category members GO Category GO:0048514 blood vessel morphogenesis Database 0


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