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Query: ATP6V1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATP6V1A 0 1.918 -0.790 0.280 0.981 0.151 0.014

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATP6V1A Ubiquitylation K132 0.567 _DIK(gl)WDFTPCK_
ATP6V1A Ubiquitylation K139 -1.426 -0.412 _WDFTPCK(gl)NLR_
ATP6V1A Ubiquitylation K516 -0.571 _LIK(gl)DDFLQQNGYTPYDR_
ATP6V1A Ubiquitylation K393 -0.894 _VK(gl)CLGNPER_
ATP6V1A Ubiquitylation K5 -0.075 -0.921 _(ac)MDFSK(gl)LPK_

Background Information for ATP6V1A:


Pubmed-ATP6V1A »
Uniprot-ATP6V1A »
Biogrid-ATP6V1A »
ProteomicsDB-ATP6V1A »

Tumorportal-ATP6V1A »
COSMIC-ATP6V1A »
GenomeRNAi-ATP6V1A »
Genecards-ATP6V1A


Protein-protein Interactions for ATP6V1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6V1C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait SPAST Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS28 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6V1B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP6V1C2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATP6V1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_F1/V1/A1_a/bsu_nucl-bd IPR000194 0
Category members ATPase_F1/V1/A1-cplx_a/bsu_C IPR000793 0
Category members ATPase_F1_a/bsu_N IPR004100 0


Protein complexes (CORUM database) featuring ATP6V1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATP6V1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members Pathway Pathway_187 KEGG_VIBRIO_CHOLERAE_INFECTION 0 0.44
Category members Pathway Pathway_188 KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 0 0.24
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0005902 microvillus Database 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0015992 proton transport Database 0.04
Category members Pathway Pathway_189 REACTOME_INSULIN_RECEPTOR_RECYCLING 0 0
Category members Pathway Pathway_190 REACTOME_SIGNALING_BY_INSULIN_RECEPTOR 0 0
Category members Pathway Pathway_191 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS 0 0
Category members Pathway Pathway_192 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING 0 0
Category members Pathway Pathway_193 REACTOME_IRON_UPTAKE_AND_TRANSPORT 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006879 cellular iron ion homeostasis Database 0
Category members GO Category GO:0015991 ATP hydrolysis coupled proton transport Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0016469 proton-transporting two-sector ATPase complex Database 0
Category members GO Category GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Database 0
Category members GO Category GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain Database 0
Category members GO Category GO:0033180 proton-transporting V-type ATPase, V1 domain Database 0
Category members GO Category GO:0033572 transferrin transport Database 0
Category members GO Category GO:0046034 ATP metabolic process Database 0
Category members GO Category GO:0046961 proton-transporting ATPase activity, rotational mechanism Database 0
Category members GO Category GO:0051701 interaction with host Database 0


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