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Query: APBB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
APBB2 1 2.858 0.800 -0.750

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
APBB2 Phosphorylation S123 1.522 1.336 _NLS(ph)PTAVINITSEK_

Background Information for APBB2:


Pubmed-APBB2 »
Uniprot-APBB2 »
Biogrid-APBB2 »
ProteomicsDB-APBB2 »

Tumorportal-APBB2 »
COSMIC-APBB2 »
GenomeRNAi-APBB2 »
Genecards-APBB2


Protein-protein Interactions for APBB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MRPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait ADCYAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APBB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LDHAL6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QTRT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WISP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in APBB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15
Category members PTB/PI_dom IPR006020 0
Category members PTB IPR013625 0


Protein complexes (CORUM database) featuring APBB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring APBB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0001540 beta-amyloid binding Database 0
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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