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Query: AATF

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AATF 0 1.958 0.062 0.323

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AATF Ubiquitylation K496 0.572 _QWLAIQK(gl)LR_
AATF Phosphorylation S203 0.544 0.457 _AGDRNS(ph)EDDGVVMTFSSVK_
AATF Ubiquitylation K475 0.282 _K(gl)TSSLDPNDQVAMGR_
AATF Ubiquitylation K283 0.128 _ALK(gl)ALLR_

Background Information for AATF:


Pubmed-AATF »
Uniprot-AATF »
Biogrid-AATF »
ProteomicsDB-AATF »

Tumorportal-AATF »
COSMIC-AATF »
GenomeRNAi-AATF »
Genecards-AATF


Protein-protein Interactions for AATF
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RTEL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF324B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AATF
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring AATF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AATF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0040016 embryonic cleavage Database 1.36
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0042254 ribosome biogenesis Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_406 PID_RB_1PATHWAY 0 0.21
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members GO Category GO:0043522 leucine zipper domain binding Database 0.15
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0048156 tau protein binding Database 0.11
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007346 regulation of mitotic cell cycle Database 0
Category members GO Category GO:0032929 negative regulation of superoxide anion generation Database 0
Category members GO Category GO:0042985 negative regulation of amyloid precursor protein biosynthetic process Database 0


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