RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
MAPK14	2	-0.160	-0.350
CAMK2G	2	-2.070	4.160
CAMK2G	2	-2.070	4.160
CAMK2G	2	-2.070	4.160		-0.654	0.073
CAMK2G	2	-2.070	4.160				0.559	1.698
CAMK2B	1	1.200	-0.790
CAMK2B	1	1.200	-0.790		-0.654	0.073
CAMK2B	1	1.200	-0.790	-0.619			0.544	0.125
CAMK2B	1	1.200	-0.790				0.559	1.698
PRKAR1A	1	-0.550	0.230
PRKAR1A	1	-0.550	0.230
PRKAR1B	1	0.660	-0.470
PRKAR1B	1	0.660	-0.470
PRKAR2B	0	-0.290	0.380
CAMK2A	0	-0.430	0.130		-0.654	0.073
CAMK2A	0	-0.430	0.130	-0.619			0.544	0.125
GNAS	0	0.840	-0.750
GNAS	0	0.840	-0.750
GNAS	0	0.840	-0.750	-0.166	-0.094	0.032	0.420	0.504
MAPK3	0
PRKAR2A	0	-0.530	1.080	0.026	-1.317	-0.866	0.783	0.007
PRKAR2A	0	-0.530	1.080
SOS1	0	0.500	-0.620	-0.570
RPS6KA1	0	-0.160	-0.660
RPS6KA1	0	-0.160	-0.660
CREB1	0	1.080	-0.800			-1.027
PIK3CA	0
RAC1	0	-0.580	1.580	0.486			-0.364	-0.568
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PRKACB	0	1.740	-1.200		-1.064
PRKACB	0	1.740	-1.200		-1.005	-0.697	0.234	0.487
CAMK2D	0	-0.260	0.500		-0.654	0.073
CAMK2D	0	-0.260	0.500	-0.619			0.544	0.125
CAMK2D	0	-0.260	0.500
PIK3R1	0	1.910	-1.220				-0.441	0.147
PRKCA	0	0.750	-0.690				0.349	0.585
PRKCA	0	0.750	-0.690
PRKCB	0	0.260	-0.530
PRKCB	0	0.260	-0.530				0.349	0.585
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
CAMK2A	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2B	Ubiquitylation	K147		-1.064	_DLKPENLLLASK(gl)CK_
CAMK2B	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2D	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2D	Phosphorylation	S330	0.412	0.370	_KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D	Phosphorylation	T331		-0.174	_KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D	Phosphorylation	T336	0.615	0.376	_ESTESSNT(ph)TIEDEDVK_
CAMK2D	Phosphorylation	T337	0.450		_ESTESSNTT(ph)IEDEDVK_
CAMK2G	Ubiquitylation	K147		-1.064	_DLKPENLLLASK(gl)CK_
CAMK2G	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2G	Phosphorylation	S365		0.765	_GSTES(ph)CNTTTEDEDLK_
CREB1	Phosphorylation	S271	-0.979	-1.450	_TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1	Ubiquitylation	K333	1.343		_ALK(gl)DLYCHK_
GNAS	Ubiquitylation	K8	0.430	0.328	_GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS	Ubiquitylation	K17	-0.011		_GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS	Ubiquitylation	K32	0.249	-0.446	_QLQK(gl)DKQVYR_
GNAS	Ubiquitylation	K58	-1.182	0.161	_STIVK(gl)QM(ox)R_
GNAS	Ubiquitylation	K92	-1.333	-0.290	_ATK(gl)VQDIKNNLK_
GNAS	Ubiquitylation	K97		0.076	_VQDIK(gl)NNLK_
GNAS	Ubiquitylation	K167	-1.721		_LHALK(gl)LR_
GNAS	Ubiquitylation	K301	-0.955	-0.198	_QDLLAEK(gl)VLAGK_
GNAS	Ubiquitylation	K308		-0.472	_SK(gl)IEDYFPEFAR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
MAPK14	Phosphorylation	S2	3.221	3.623	_(ac)S(ph)QERPTFYR_
MAPK14	Phosphorylation	T180	0.958	1.087	_HTDDEM(ox)T(ph)GYVATR_
MAPK14	Phosphorylation	Y182	1.388	1.374	_HTDDEM(ox)TGY(ph)VATR_
MAPK14	Ubiquitylation	K249	0.073	-1.380	_LVGTPGAELLKK(gl)_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PRKACB	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACB	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PRKACB	Phosphorylation	T243		-0.835	_T(ph)WTLCGTPEYLAPEIILSK_
PRKACB	Phosphorylation	T245	-0.116	-0.102	_TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A	Ubiquitylation	K63	-1.895		_LEKEEAK(gl)QIQNLQK_
PRKAR1A	Ubiquitylation	K70	-0.869	0.073	_QIQNLQK(gl)AGTR_
PRKAR1A	Phosphorylation	S83	-0.969	-0.776	_EDEIS(ph)PPPPNPVVK_
PRKAR1A	Ubiquitylation	K92	-3.269	-2.395	_TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A	Ubiquitylation	K222	0.412	0.536	_TNVK(gl)LWGIDR_
PRKAR1A	Ubiquitylation	K244	-0.384	3.721	_K(gl)MYEEFLSK_
PRKAR1A	Ubiquitylation	K261	-0.886		_VSILESLDK(gl)WER_
PRKAR1A	Ubiquitylation	K346		0.329	_GPLK(gl)CVK_
PRKAR1A	Ubiquitylation	K349	-0.425	-0.103	_CVK(gl)LDRPR_
PRKAR1A	Ubiquitylation	K367	-0.939	0.044	_VLGPCSDILK(gl)R_
PRKAR1B	Phosphorylation	S3	0.185	0.343	_(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B	Ubiquitylation	K244	-0.384	3.721	_K(gl)MYEEFLSK_
PRKAR1B	Ubiquitylation	K346		0.329	_GPLK(gl)CVK_
PRKAR1B	Ubiquitylation	K349	-0.425	-0.103	_CVK(gl)LDRPR_
PRKAR2A	Phosphorylation	S99	0.020	0.056	_RVS(ph)VCAETYNPDEEEEDTDPR_
PRKAR2A	Phosphorylation	T104	-0.175		_RVSVCAET(ph)YNPDEEEEDTDPR_
PRKAR2A	Ubiquitylation	K359	0.640		_GQYFGELALVTNK(gl)PR_
PRKAR2B	Phosphorylation	T69		-0.367	_TWGDLGAAAGGGT(ph)PSK_
PRKAR2B	Phosphorylation	S114	0.366	0.525	_RAS(ph)VCAEAYNPDEEEDDAESR_
PRKAR2B	Ubiquitylation	K359	0.640		_GQYFGELALVTNK(gl)PR_
PRKCA	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCA	Ubiquitylation	K316	-0.522	-0.535	_LGPAGNK(gl)VISPSEDR_
PRKCB	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCB	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCB	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCB	Ubiquitylation	K315	0.213	0.518	_ISQGTK(gl)VPEEK_
RAC1	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC1	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC1	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC1	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC1	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC1	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC1	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC1	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RPS6KA1	Phosphorylation	S227	0.363	0.496	_AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA1	Phosphorylation	T231	0.315		_KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA1	Ubiquitylation	K316		-1.156	_LGSGPDGAEEIK(gl)R_
RPS6KA1	Phosphorylation	T359	-0.149	-0.339	_T(ph)PKDSPGIPPSAGAHQLFR_
RPS6KA1	Phosphorylation	S363	-0.711	-0.697	_TPKDS(ph)PGIPPSAGAHQLFR_
RPS6KA1	Ubiquitylation	K566		-0.152	_ICDFGFAK(gl)QLR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_