Results for the Category
negative regulation of insulin secretion
(GO:0046676)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
HADH | 1 | -0.250 | -0.080 | 2.056 | 0.819 | 0.176 | ||
PFKL | 1 | -0.440 | 0.680 | 0.869 | 1.217 | 0.915 | ||
UTS2 | 0 | -0.560 | 0.180 | -0.048 | 0.360 | |||
SREBF1 | 0 | 0.540 | -0.490 | |||||
SREBF1 | 0 | 0.540 | -0.490 | |||||
REST | 0 | -0.120 | -0.050 | -0.002 | -1.235 | -0.636 | ||
PSMD9 | 0 | -0.440 | 1.070 | |||||
PPP3CA | 0 | 1.550 | -1.230 | -0.298 | 1.130 | |||
PPP3CA | 0 | 1.550 | -1.230 | 0.923 | 0.537 | |||
IRS1 | 0 | |||||||
PTPN11 | 0 | -0.210 | -0.400 | 0.644 | 1.053 | 0.451 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
IRS1 | Phosphorylation | S1101 | -0.078 | _HSS(ph)ETFSSTPSATR_ | |
PFKL | Ubiquitylation | K365 | -0.860 | _AMDDK(gl)RFDEATQLR_ | |
PFKL | Ubiquitylation | K469 | 0.001 | _GGSMLGTK(gl)R_ | |
PFKL | Ubiquitylation | K616 | 0.588 | -0.447 | _MK(gl)TDIQR_ |
PFKL | Ubiquitylation | K677 | 0.140 | -0.035 | _NYGTK(gl)LGVK_ |
PFKL | Phosphorylation | S775 | 1.454 | 1.553 | _RTLS(ph)MDKGF_ |
PPP3CA | Ubiquitylation | K32 | -0.137 | _LTAK(gl)EVFDNDGKPR_ | |
PPP3CA | Ubiquitylation | K56 | 0.132 | _VDVLK(gl)NHLVK_ | |
PPP3CA | Ubiquitylation | K323 | 0.705 | _AAVLK(gl)YENNVMNIR_ | |
PPP3CA | Ubiquitylation | K405 | 0.078 | _AIGK(gl)MAR_ | |
PSMD9 | Ubiquitylation | K117 | 0.095 | _DMAEAHK(gl)EAMSR_ | |
PSMD9 | Ubiquitylation | K123 | -1.236 | -0.524 | _K(gl)LGQSESQGPPR_ |
PTPN11 | Ubiquitylation | K124 | 0.562 | _EAEK(gl)LLTEK_ | |
REST | Ubiquitylation | K280 | 0.406 | _VYTCGK(gl)CNYFSDR_ | |
REST | Phosphorylation | S864 | -3.456 | _ESVSTEDLSPPS(ph)PPLPK_ | |
SREBF1 | Ubiquitylation | K321 | -0.637 | _LAAGSK(gl)APASAQSR_ | |
SREBF1 | Ubiquitylation | K579 | -1.649 | 0.673 | _K(gl)QADLDLAR_ |
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