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negative regulation of insulin secretion
(GO:0046676)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HADH 1 -0.250 -0.080 2.056 0.819 0.176
PFKL 1 -0.440 0.680 0.869 1.217 0.915
UTS2 0 -0.560 0.180 -0.048 0.360
SREBF1 0 0.540 -0.490
SREBF1 0 0.540 -0.490
REST 0 -0.120 -0.050 -0.002 -1.235 -0.636
PSMD9 0 -0.440 1.070
PPP3CA 0 1.550 -1.230 -0.298 1.130
PPP3CA 0 1.550 -1.230 0.923 0.537
IRS1 0
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
IRS1 Phosphorylation S1101 -0.078 _HSS(ph)ETFSSTPSATR_
PFKL Ubiquitylation K365 -0.860 _AMDDK(gl)RFDEATQLR_
PFKL Ubiquitylation K469 0.001 _GGSMLGTK(gl)R_
PFKL Ubiquitylation K616 0.588 -0.447 _MK(gl)TDIQR_
PFKL Ubiquitylation K677 0.140 -0.035 _NYGTK(gl)LGVK_
PFKL Phosphorylation S775 1.454 1.553 _RTLS(ph)MDKGF_
PPP3CA Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CA Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CA Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CA Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PSMD9 Ubiquitylation K117 0.095 _DMAEAHK(gl)EAMSR_
PSMD9 Ubiquitylation K123 -1.236 -0.524 _K(gl)LGQSESQGPPR_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
REST Ubiquitylation K280 0.406 _VYTCGK(gl)CNYFSDR_
REST Phosphorylation S864 -3.456 _ESVSTEDLSPPS(ph)PPLPK_
SREBF1 Ubiquitylation K321 -0.637 _LAAGSK(gl)APASAQSR_
SREBF1 Ubiquitylation K579 -1.649 0.673 _K(gl)QADLDLAR_


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