Results for the Category
DIABETES MELLITUS NONINSULIN-DEPENDENT
(DIABETES_MELLITUS_NONINSULIN-DEPENDENT)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| INSR | 2 | -0.850 | 0.830 | 1.143 | 0.785 | |||
| AKT2 | 0 | -1.420 | 2.210 | -0.194 | ||||
| CDKAL1 | 0 | 0.070 | 0.220 | 0.046 | 0.108 | |||
| TCF7L2 | 0 | -0.550 | 0.790 | -0.741 | ||||
| INPPL1 | 0 | 1.690 | -0.810 | |||||
| IRS1 | 0 | |||||||
| ENPP1 | 0 | 0.220 | -0.270 | -0.295 | 1.478 | 0.914 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| AKT2 | Ubiquitylation | K14 | 0.306 | 0.070 | _EGWLHK(gl)R_ |
| AKT2 | Ubiquitylation | K111 | 1.082 | _AIQMVANSLK(gl)QR_ | |
| AKT2 | Ubiquitylation | K160 | 0.251 | _LLGK(gl)GTFGK_ | |
| AKT2 | Phosphorylation | T451 | -0.091 | -0.612 | _YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_ |
| AKT2 | Phosphorylation | Y456 | -0.265 | _YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_ | |
| CDKAL1 | Phosphorylation | S3 | 1.102 | _PS(ph)ASCDTLLDDIEDIVSQEDSKPQDR_ | |
| CDKAL1 | Phosphorylation | S5 | 0.811 | _PSAS(ph)CDTLLDDIEDIVSQEDSKPQDR_ | |
| CDKAL1 | Ubiquitylation | K343 | 0.633 | _EYCVADFK(gl)R_ | |
| CDKAL1 | Ubiquitylation | K496 | -1.923 | _GQPVSDAK(gl)VYTPSISKPLAK_ | |
| CDKAL1 | Ubiquitylation | K516 | 0.544 | 0.286 | _GEVSGLTK(gl)DFR_ |
| INPPL1 | Phosphorylation | S1003 | -1.290 | _NSFNNPAYYVLEGVPHQLLPPEPPS(ph)PAR_ | |
| INSR | Ubiquitylation | K1022 | -0.603 | _EK(gl)ITLLR_ | |
| INSR | Ubiquitylation | K1047 | 0.305 | 0.711 | _DIIK(gl)GEAETR_ |
| INSR | Ubiquitylation | K1057 | 0.482 | 0.484 | _VAVK(gl)TVNESASLR_ |
| INSR | Ubiquitylation | K1352 | 1.606 | 2.754 | _DGGSSLGFK(gl)R_ |
| IRS1 | Phosphorylation | S1101 | -0.078 | _HSS(ph)ETFSSTPSATR_ | |
| TCF7L2 | Ubiquitylation | K88 | -0.867 | -0.222 | _ESLEEAAK(gl)R_ |
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