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Query: CDKAL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDKAL1 0 2.653 0.070 0.220 0.046 0.108

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDKAL1 Phosphorylation S3 1.102 _PS(ph)ASCDTLLDDIEDIVSQEDSKPQDR_
CDKAL1 Phosphorylation S5 0.811 _PSAS(ph)CDTLLDDIEDIVSQEDSKPQDR_
CDKAL1 Ubiquitylation K343 0.633 _EYCVADFK(gl)R_
CDKAL1 Ubiquitylation K516 0.544 0.286 _GEVSGLTK(gl)DFR_
CDKAL1 Ubiquitylation K496 -1.923 _GQPVSDAK(gl)VYTPSISKPLAK_

Background Information for CDKAL1:


Pubmed-CDKAL1 »
Uniprot-CDKAL1 »
Biogrid-CDKAL1 »
ProteomicsDB-CDKAL1 »

Tumorportal-CDKAL1 »
COSMIC-CDKAL1 »
GenomeRNAi-CDKAL1 »
Genecards-CDKAL1


Protein-protein Interactions for CDKAL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MMS19 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMS19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDKAL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TRAM_dom IPR002792 0
Category members Methylthiotransferase IPR005839 0
Category members Elp3/MiaB/NifB IPR006638 0
Category members rSAM IPR007197 0
Category members Methylthiotransferase_N IPR013848 0


Protein complexes (CORUM database) featuring CDKAL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDKAL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0008033 tRNA processing Database 0.39
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members Disease phenotype DIABETES_MELLITUS_NONINSULIN-DEPENDENT DIABETES MELLITUS NONINSULIN-DEPENDENT Database 0.05
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0009451 RNA modification Database 0
Category members GO Category GO:0043412 macromolecule modification Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051536 iron-sulfur cluster binding Database 0
Category members GO Category GO:0051539 4 iron, 4 sulfur cluster binding Database 0


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