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Query: YBX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YBX1 2 8.414 -0.180 -0.010 -0.197 -0.190 -1.344 -0.617

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YBX1 Ubiquitylation K64 5.830 4.056 _VLGTVK(gl)WFNVR_
YBX1 Ubiquitylation K170 -0.297 0.298 _NYQQNYQNSESGEK(gl)NEGSESAPEGQAQQR_
YBX1 Phosphorylation S174 0.041 0.228 _NEGS(ph)ESAPEGQAQQR_
YBX1 Phosphorylation S165 0.119 0.151 _NYQQNYQNS(ph)ESGEK_
YBX1 Ubiquitylation K137 -0.751 0.084 _GAEAANVTGPGGVPVQGSK(gl)YAADR_
YBX1 Phosphorylation S176 0.061 0.075 _NEGSES(ph)APEGQAQQR_
YBX1 Phosphorylation S209 0.658 -0.148 _RPQYS(ph)NPPVQGEVM(ox)EGADNQGAGEQGRPVR_
YBX1 Phosphorylation Y162 -0.210 _NYQQNY(ph)QNSESGEKNEGSESAPEGQAQQR_

Background Information for YBX1:


Pubmed-YBX1 »
Uniprot-YBX1 »
Biogrid-YBX1 »
ProteomicsDB-YBX1 »

Tumorportal-YBX1 »
COSMIC-YBX1 »
GenomeRNAi-YBX1 »
Genecards-YBX1


Protein-protein Interactions for YBX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait BHLHA15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPSA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SURF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THUMPD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3HAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF324B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YBX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members CSP_DNA-bd IPR002059 0.04
Category members Cold_shock_prot IPR011129 0.04


Protein complexes (CORUM database) featuring YBX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 2156 YBX1-AKT1 complex Database 0.29
Category members Corum 430 18S U11/U12 snRNP Database 0.29
Category members Corum 1068 12S U11 snRNP Database 0.17


Categories featuring YBX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0070934 CRD-mediated mRNA stabilization Database 0.7
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0070937 CRD-mediated mRNA stability complex Database 0.44
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_602 PID_PTP1B_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0051154 negative regulation of striated muscle cell differentiation Database 0
Category members GO Category GO:0051781 positive regulation of cell division Database 0
Category members GO Category GO:0071204 histone pre-mRNA 3'end processing complex Database 0


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