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Query: WAC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WAC 1 1.415 1.080 -0.710 -2.718 0.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WAC Phosphorylation T293 2.401 1.442 _LPT(ph)PTSSVPAQK_
WAC Phosphorylation S64 0.472 0.441 _SDS(ph)PENKYSDSTGHSK_
WAC Phosphorylation S511 1.112 0.116 _QQGHEPVS(ph)PR_
WAC Phosphorylation S53 0.433 0.072 _MRDAGDPS(ph)PPNK_

Background Information for WAC:


Pubmed-WAC »
Uniprot-WAC »
Biogrid-WAC »
ProteomicsDB-WAC »

Tumorportal-WAC »
COSMIC-WAC »
GenomeRNAi-WAC »
Genecards-WAC


Protein-protein Interactions for WAC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKN2AIPNL Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WAC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WAC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15


Protein complexes (CORUM database) featuring WAC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WAC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0010390 histone monoubiquitination Database 1.39
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0000993 RNA polymerase II core binding Database 0.91
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0016239 positive regulation of macroautophagy Database 0.09
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0


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