Results for the Category
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032435)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| WAC | 1 | 1.080 | -0.710 | -2.718 | 0.290 | |||
| HSP90AB1 | 1 | 1.280 | -1.050 | 0.283 | 0.786 | -1.175 | 0.317 | 0.463 |
| N4BP1 | 1 | -1.890 | 2.620 | |||||
| N4BP1 | 1 | -0.940 | 0.710 | |||||
| SENP1 | 0 | -1.070 | 0.900 | 0.519 | 0.698 | |||
| GIPC1 | 0 | 0.050 | -0.100 | |||||
| TLK2 | 0 | -0.170 | -0.340 | 0.092 | ||||
| UBXN1 | 0 | 0.810 | -0.820 | -0.696 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| GIPC1 | Ubiquitylation | K80 | 0.463 | _IEGFTNVK(gl)ELYGK_ | |
| GIPC1 | Ubiquitylation | K199 | -0.691 | -0.589 | _LLK(gl)ELPR_ |
| GIPC1 | Ubiquitylation | K210 | -0.064 | _TFTLK(gl)LTEPR_ | |
| HSP90AB1 | Ubiquitylation | K64 | 0.829 | -0.090 | _YESLTDPSK(gl)LDSGKELK_ |
| HSP90AB1 | Ubiquitylation | K69 | 0.661 | 0.380 | _LDSGK(gl)ELK_ |
| HSP90AB1 | Ubiquitylation | K72 | -1.242 | -0.130 | _ELK(gl)IDIIPNPQER_ |
| HSP90AB1 | Phosphorylation | S226 | 0.404 | 0.704 | _EKEIS(ph)DDEAEEEK_ |
| HSP90AB1 | Phosphorylation | S255 | 0.525 | 0.628 | _IEDVGS(ph)DEEDDSGKDKK_ |
| HSP90AB1 | Phosphorylation | S261 | 0.520 | 0.624 | _IEDVGSDEEDDS(ph)GKDK_ |
| HSP90AB1 | Ubiquitylation | K347 | 0.110 | _RAPFDLFENK(gl)K_ | |
| HSP90AB1 | Ubiquitylation | K348 | -0.096 | _RAPFDLFENKK(gl)_ | |
| HSP90AB1 | Ubiquitylation | K428 | 0.308 | _K(gl)FYEAFSK_ | |
| HSP90AB1 | Ubiquitylation | K435 | 0.847 | 0.933 | _FYEAFSK(gl)NLK_ |
| HSP90AB1 | Ubiquitylation | K438 | 1.021 | -0.058 | _NLK(gl)LGIHEDSTNR_ |
| HSP90AB1 | Ubiquitylation | K481 | 0.811 | _MKETQK(gl)SIYYITGESK_ | |
| HSP90AB1 | Ubiquitylation | K491 | 0.982 | 1.512 | _SIYYITGESK(gl)EQVANSAFVER_ |
| HSP90AB1 | Ubiquitylation | K531 | 0.745 | 1.350 | _EFDGK(gl)SLVSVTK_ |
| HSP90AB1 | Ubiquitylation | K559 | 0.847 | 1.549 | _AK(gl)FENLCK_ |
| HSP90AB1 | Ubiquitylation | K565 | -0.066 | _FENLCK(gl)LMK_ | |
| HSP90AB1 | Ubiquitylation | K573 | 0.243 | 0.360 | _EILDK(gl)KVEK_ |
| HSP90AB1 | Ubiquitylation | K574 | 0.241 | 0.550 | _EILDKK(gl)VEK_ |
| HSP90AB1 | Ubiquitylation | K623 | 0.520 | 1.081 | _DNSTMGYM(ox)MAK(gl)K_ |
| N4BP1 | Phosphorylation | T242 | 0.090 | 0.086 | _AGT(ph)PVSELTK_ |
| N4BP1 | Phosphorylation | S300 | 0.738 | 1.001 | _KQFS(ph)LENVQEGEILHDAK_ |
| N4BP1 | Ubiquitylation | K412 | 0.502 | _NK(gl)GVYSSTNELTTDSTPK_ | |
| SENP1 | Ubiquitylation | K231 | -0.099 | _NTLK(gl)DSLFK_ | |
| TLK2 | Phosphorylation | T98 | 0.262 | _ISDYFEFAGGSAPGT(ph)SPGR_ | |
| TLK2 | Phosphorylation | S99 | 0.267 | -0.122 | _ISDYFEFAGGSAPGTS(ph)PGR_ |
| UBXN1 | Ubiquitylation | K83 | -1.791 | _EPTSSEQGGLEGSGSAAGEGK(gl)PALSEEER_ | |
| UBXN1 | Ubiquitylation | K96 | -1.483 | _EPTSSEQGGLEGSGSAAGEGKPALSEEERQEQTK(gl)R_ | |
| UBXN1 | Ubiquitylation | K105 | 0.343 | 0.709 | _RM(ox)LELVAQK(gl)QR_ |
| UBXN1 | Ubiquitylation | K154 | 1.029 | 0.790 | _EK(gl)AEELAAR_ |
| UBXN1 | Ubiquitylation | K178 | -4.185 | _K(gl)YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR_ | |
| UBXN1 | Phosphorylation | S200 | -1.255 | -2.127 | _KYGGSVGSQPPPVAPEPGPVPSS(ph)PSQEPPTKR_ |
| WAC | Phosphorylation | S53 | 0.433 | 0.072 | _MRDAGDPS(ph)PPNK_ |
| WAC | Phosphorylation | S64 | 0.472 | 0.441 | _SDS(ph)PENKYSDSTGHSK_ |
| WAC | Phosphorylation | T293 | 2.401 | 1.442 | _LPT(ph)PTSSVPAQK_ |
| WAC | Phosphorylation | S511 | 1.112 | 0.116 | _QQGHEPVS(ph)PR_ |
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