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Query: VPS33B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS33B 1 1.641 0.750 -0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VPS33B Ubiquitylation K321 1.641 _GMDIK(gl)QMK_
VPS33B Ubiquitylation K504 -0.823 -0.779 _VDGEYDLK(gl)VPR_
VPS33B Ubiquitylation K480 -0.791 _ITDAFSSLAK(gl)R_

Background Information for VPS33B:


Pubmed-VPS33B »
Uniprot-VPS33B »
Biogrid-VPS33B »
ProteomicsDB-VPS33B »

Tumorportal-VPS33B »
COSMIC-VPS33B »
GenomeRNAi-VPS33B »
Genecards-VPS33B


Protein-protein Interactions for VPS33B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLT25D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MATN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSFA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS33B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sec1-like IPR001619 1.02


Protein complexes (CORUM database) featuring VPS33B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VPS33B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0061025 membrane fusion Database 0.93
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0006904 vesicle docking involved in exocytosis Database 0.51
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0032418 lysosome localization Database 0.32
Category members Disease phenotype Arthrogryposis_-_renal_dysfunction_-_cholestasis Arthrogryposis - renal dysfunction - cholestasis Database 0.24
Category members GO Category GO:0030897 HOPS complex Database 0.13
Category members GO Category GO:0005770 late endosome Database 0.09
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0031091 platelet alpha granule Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0032400 melanosome localization Database 0
Category members GO Category GO:0070889 platelet alpha granule organization Database 0


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