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Query: USP33

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP33 0 -0.304 0.750 -0.150

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP33 Ubiquitylation K882 -0.583 0.278 _IAVTK(gl)CGNVMLR_
USP33 Ubiquitylation K371 -0.567 _MCNK(gl)INK_

Background Information for USP33:


Pubmed-USP33 »
Uniprot-USP33 »
Biogrid-USP33 »
ProteomicsDB-USP33 »

Tumorportal-USP33 »
COSMIC-USP33 »
GenomeRNAi-USP33 »
Genecards-USP33


Protein-protein Interactions for USP33
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APBA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGRRF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPCAT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OBFC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKTL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TLR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP33
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Pept_C19_DUSP IPR006615 0.23
Category members Znf_UBP IPR001607 0.05


Protein complexes (CORUM database) featuring USP33
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5267 VHL-VDU1-TCEB1-TCEB2 complex Database 0


Categories featuring USP33
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0071108 protein K48-linked deubiquitination Database 0.88
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0070536 protein K63-linked deubiquitination Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0001664 G-protein coupled receptor binding Database 0.09
Category members GO Category GO:0008277 regulation of G-protein coupled receptor protein signaling pathway Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030891 VCB complex Database 0
Category members GO Category GO:0044297 cell body Database 0
Category members GO Category GO:0051298 centrosome duplication Database 0


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