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Query: UPF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UPF2 0 -0.799 0.020 -0.140 -0.668 -0.131

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for UPF2:


Pubmed-UPF2 »
Uniprot-UPF2 »
Biogrid-UPF2 »
ProteomicsDB-UPF2 »

Tumorportal-UPF2 »
COSMIC-UPF2 »
GenomeRNAi-UPF2 »
Genecards-UPF2


Protein-protein Interactions for UPF2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait UPF3B Cat. description Hein, Mann, Cell 2015


Protein Domains in UPF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members MIF4G-like_typ-3 IPR003890 0


Protein complexes (CORUM database) featuring UPF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 822 mRNA decay complex (UPF1, UPF2, UPF3B, DCP2, XRN1, XRN2, EXOSC2, EXOSC4, EXOSC10, PARN) Database 1.39
Category members Corum 812 Upf complex (UPF1, UPF2, UPF3a) Database 0.26
Category members Corum 813 Upf complex (UPF1, UPF2, UPF3b) Database 0.26
Category members Corum 814 Postsplicing complex Database 0.01


Categories featuring UPF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0001889 liver development Database 0.51
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0035145 exon-exon junction complex Database 0.28
Category members GO Category GO:0031100 organ regeneration Database 0.01


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