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Query: TUBG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TUBG1 0 -0.399 -0.710 1.260 -0.141 -0.630 -0.211 -0.844 -0.821

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TUBG1 Ubiquitylation K287 1.041 -0.053 _K(gl)TTVLDVMR_
TUBG1 Ubiquitylation K301 0.057 -0.550 _LLQPK(gl)NVMVSTGR_

Background Information for TUBG1:


Pubmed-TUBG1 »
Uniprot-TUBG1 »
Biogrid-TUBG1 »
ProteomicsDB-TUBG1 »

Tumorportal-TUBG1 »
COSMIC-TUBG1 »
GenomeRNAi-TUBG1 »
Genecards-TUBG1


Protein-protein Interactions for TUBG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM83D Cat. description Hein, Mann, Cell 2015
Category members IP bait FLII Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRWD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MZT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MZT2A Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRICKLE3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SCAF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait TMPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MZT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MZT2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBGCP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TUBG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tubulin IPR000217 0
Category members Alpha_tubulin IPR002452 0
Category members Beta_tubulin IPR002453 0
Category members Gamma_tubulin IPR002454 0
Category members Delta_tubulin IPR002967 0
Category members Tubulin_FtsZ_GTPase IPR003008 0
Category members Epsilon_tubulin IPR004057 0
Category members Tub_FtsZ_C IPR008280 0
Category members Tubulin/FtsZ_2-layer-sand-dom IPR018316 0
Category members Misato_II_tubulin-like IPR019605 0


Protein complexes (CORUM database) featuring TUBG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TUBG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0000794 condensed nuclear chromosome Database 1.58
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005876 spindle microtubule Database 0.68
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0036064 ciliary basal body Database 0.05
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members Pathway Pathway_1252 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES 0 0
Category members GO Category GO:0000212 meiotic spindle organization Database 0
Category members GO Category GO:0000242 pericentriolar material Database 0
Category members GO Category GO:0000930 gamma-tubulin complex Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0005827 polar microtubule Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0007020 microtubule nucleation Database 0
Category members GO Category GO:0031122 cytoplasmic microtubule organization Database 0
Category members GO Category GO:0031513 nonmotile primary cilium Database 0
Category members GO Category GO:0045177 apical part of cell Database 0
Category members GO Category GO:0051258 protein polymerization Database 0


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