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Query: TOB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TOB1 0 0.044 1.290 -1.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TOB1 Phosphorylation T204 -0.200 0.244 _T(ph)SPINLGLNVNDLLK_
TOB1 Phosphorylation S205 -0.200 0.244 _T(ph)SPINLGLNVNDLLK_

Background Information for TOB1:


Pubmed-TOB1 »
Uniprot-TOB1 »
Biogrid-TOB1 »
ProteomicsDB-TOB1 »

Tumorportal-TOB1 »
COSMIC-TOB1 »
GenomeRNAi-TOB1 »
Genecards-TOB1


Protein-protein Interactions for TOB1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TOB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Anti_prolifrtn IPR002087 0.09


Protein complexes (CORUM database) featuring TOB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TOB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0045668 negative regulation of osteoblast differentiation Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0007184 SMAD protein import into nucleus Database 0.08
Category members Pathway Pathway_903 BIOCARTA_TOB1_PATHWAY 0 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0030014 CCR4-NOT complex Database 0
Category members GO Category GO:0030514 negative regulation of BMP signaling pathway Database 0
Category members GO Category GO:0030971 receptor tyrosine kinase binding Database 0
Category members GO Category GO:0046332 SMAD binding Database 0
Category members GO Category GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Database 0


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