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Query: TIA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TIA1 0 2.450 -1.050 1.250
TIA1 0 2.450 -1.050 1.250 -0.721 -0.259 -0.319 -0.332 -0.199
TIA1 0 2.450 -1.050 1.250 -0.455 0.130 0.623

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TIA1 Ubiquitylation K91 0.902 _VNWATTPSSQKK(gl)_

Background Information for TIA1:


Pubmed-TIA1 »
Uniprot-TIA1 »
Biogrid-TIA1 »
ProteomicsDB-TIA1 »

Tumorportal-TIA1 »
COSMIC-TIA1 »
GenomeRNAi-TIA1 »
Genecards-TIA1


Protein-protein Interactions for TIA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85 Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ELL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NETO2 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait SMEK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015


Protein Domains in TIA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members RRM_dom_euk IPR003954 0.18


Protein complexes (CORUM database) featuring TIA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TIA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008143 poly(A) RNA binding Database 0.44
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0042036 negative regulation of cytokine biosynthetic process Database 0.04
Category members GO Category GO:0017091 AU-rich element binding Database 0
Category members GO Category GO:0048024 regulation of mRNA splicing, via spliceosome Database 0


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