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Query: SLC3A2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC3A2 0 4.784 -0.520 0.660 0.690 1.007 -1.149 0.607 0.589

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC3A2 Phosphorylation T106 1.017 _(ac)S(ph)QDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEK_
SLC3A2 Ubiquitylation K145 1.389 0.982 _NGLVK(gl)IK_
SLC3A2 Phosphorylation S103 0.947 _(ac)S(ph)QDTEVDMKEVELNELEPEK_
SLC3A2 Ubiquitylation K147 1.147 0.705 _IK(gl)VAEDEAEAAAAAK_
SLC3A2 Ubiquitylation K166 -0.293 0.631 _FTGLSK(gl)EELLK_
SLC3A2 Ubiquitylation K160 -0.471 _VAEDEAEAAAAAK(gl)FTGLSK_

Background Information for SLC3A2:


Pubmed-SLC3A2 »
Uniprot-SLC3A2 »
Biogrid-SLC3A2 »
ProteomicsDB-SLC3A2 »

Tumorportal-SLC3A2 »
COSMIC-SLC3A2 »
GenomeRNAi-SLC3A2 »
Genecards-SLC3A2


Protein-protein Interactions for SLC3A2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATXN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MBOAT1 Cat. description Hein, Mann, Cell 2015


Protein Domains in SLC3A2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_13_cat_dom IPR006047 0
Category members Glyco_hydro_13_sub_cat_dom IPR006589 0
Category members Glycoside_hydrolase_SF IPR017853 0


Protein complexes (CORUM database) featuring SLC3A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3103 ITGAV-ITGB3-SLC3A2 complex Database 0


Categories featuring SLC3A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_1307 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE 0 0.32
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_1271 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS 0 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0003725 double-stranded RNA binding Database 0.1
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members GO Category GO:0015804 neutral amino acid transport Database 0.03
Category members GO Category GO:0015175 neutral amino acid transmembrane transporter activity Database 0.02
Category members Pathway Pathway_927 REACTOME_BASIGIN_INTERACTIONS 0 0
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members Pathway Pathway_489 PID_NFAT_TFPATHWAY 0 0
Category members GO Category GO:0005432 calcium:sodium antiporter activity Database 0
Category members GO Category GO:0006816 calcium ion transport Database 0
Category members GO Category GO:0006865 amino acid transport Database 0
Category members GO Category GO:0015827 tryptophan transport Database 0
Category members GO Category GO:0016049 cell growth Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0043169 cation binding Database 0
Category members GO Category GO:0043330 response to exogenous dsRNA Database 0


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