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Query: SGPL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SGPL1 0 1.222 0.190 0.490 -0.430 0.606 0.394

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SGPL1 Ubiquitylation K228 -0.506 _DLAFEK(gl)GIK_
SGPL1 Ubiquitylation K231 -0.506 _DLAFEK(gl)GIK_
SGPL1 Ubiquitylation K107 -0.060 _NMSFLK(gl)VDKEYVK_
SGPL1 Ubiquitylation K131 0.668 _LK(gl)EYSSMDAFWQEGR_

Background Information for SGPL1:


Pubmed-SGPL1 »
Uniprot-SGPL1 »
Biogrid-SGPL1 »
ProteomicsDB-SGPL1 »

Tumorportal-SGPL1 »
COSMIC-SGPL1 »
GenomeRNAi-SGPL1 »
Genecards-SGPL1


Protein-protein Interactions for SGPL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PKN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKRD12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTN2A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISLR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEMA7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUSC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SGPL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aminotrans_V_dom IPR000192 0
Category members PyrdxlP-dep_de-COase IPR002129 0
Category members Aminotransferase_I/II IPR004839 0
Category members PyrdxlP-dep_Trfase IPR015424 0


Protein complexes (CORUM database) featuring SGPL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SGPL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_736 PID_S1P_META_PATHWAY 0 0.73
Category members GO Category GO:0008585 female gonad development Database 0.64
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0040014 regulation of multicellular organism growth Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0030149 sphingolipid catabolic process Database 0.32
Category members GO Category GO:0001553 luteinization Database 0.31
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members GO Category GO:0008210 estrogen metabolic process Database 0.07
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_127 KEGG_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_498 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS 0 0
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0006672 ceramide metabolic process Database 0
Category members GO Category GO:0006807 nitrogen compound metabolic process Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008209 androgen metabolic process Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0010761 fibroblast migration Database 0
Category members GO Category GO:0016831 carboxy-lyase activity Database 0
Category members GO Category GO:0019752 carboxylic acid metabolic process Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0030148 sphingolipid biosynthetic process Database 0
Category members GO Category GO:0030170 pyridoxal phosphate binding Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0033327 Leydig cell differentiation Database 0
Category members GO Category GO:0048008 platelet-derived growth factor receptor signaling pathway Database 0
Category members GO Category GO:0048705 skeletal system morphogenesis Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0


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