bioLOGIC-db

bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

Query: SCYL1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
W

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
SCYL1	0	0.891	0.410	-0.530	0.944

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
SCYL1	Phosphorylation	S754		-0.053	_PSTQPRPDS(ph)WGEDNWEGLETDSR_

Background Information for SCYL1:

Pubmed-SCYL1 »

Uniprot-SCYL1 »

Biogrid-SCYL1 »

ProteomicsDB-SCYL1 »

Tumorportal-SCYL1 »

COSMIC-SCYL1 »

GenomeRNAi-SCYL1 »

Genecards-SCYL1

Protein-protein Interactions for SCYL1

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CTDSPL2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RHOA	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SLC6A8	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait AGPAT3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait AURKA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait AVIL	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DUSP23	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KLHL2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SCYL1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SEC31A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in SCYL1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	ARM-type_fold	IPR016024	9.26
Category members	HEAT	IPR000357	3.83
Category members	Kinase-like_dom	IPR011009	0.03
Category members	Prot_kinase_dom	IPR000719	0
Category members	Ser-Thr/Tyr_kinase_cat_dom	IPR001245	0

Protein complexes (CORUM database) featuring SCYL1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	86	NUMAC complex (nucleosomal methylation activator complex)	Database	0.83

Categories featuring SCYL1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0005488	binding	Database	9.32
Category members	GO Category	GO:0005524	ATP binding	Database	5.54
Category members	GO Category	GO:0003677	DNA binding	Database	1.53
Category members	GO Category	GO:0006351	transcription, DNA-templated	Database	1.07
Category members	GO Category	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Database	0.74
Category members	GO Category	GO:0005815	microtubule organizing center	Database	0.39
Category members	GO Category	GO:0005794	Golgi apparatus	Database	0.27
Category members	GO Category	GO:0004672	protein kinase activity	Database	0.19
Category members	GO Category	GO:0005801	cis-Golgi network	Database	0.1
Category members	GO Category	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	Database	0.05
Category members	GO Category	GO:0006468	protein phosphorylation	Database	0.04
Category members	GO Category	GO:0004713	protein tyrosine kinase activity	Database	0.01
Category members	GO Category	GO:0006355	regulation of transcription, DNA-dependent	Database	0
Category members	GO Category	GO:0016772	transferase activity, transferring phosphorus-containing groups	Database	0
Category members	GO Category	GO:0018108	peptidyl-tyrosine phosphorylation	Database	0
Category members	GO Category	GO:0030126	COPI vesicle coat	Database	0