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Query: SAV1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SAV1 0 1.144 1.110 -0.700

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SAV1 Phosphorylation S27 1.144 _KETS(ph)PLLR_

Background Information for SAV1:





Protein-protein Interactions for SAV1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APC Cat. description Hein, Mann, Cell 2015
Category members IP bait PCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait ADCYAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOCS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS37D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF133 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF420 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF695 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SAV1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15
Category members SARAH_dom IPR011524 0


Protein complexes (CORUM database) featuring SAV1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SAV1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0035329 hippo signaling Database 0.68
Category members Pathway Pathway_1013 REACTOME_SIGNALING_BY_HIPPO 0 0.63
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0050680 negative regulation of epithelial cell proliferation Database 0.19
Category members GO Category GO:0060044 negative regulation of cardiac muscle cell proliferation Database 0.06
Category members GO Category GO:0046620 regulation of organ growth Database 0.03
Category members GO Category GO:0001942 hair follicle development Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0060412 ventricular septum morphogenesis Database 0
Category members GO Category GO:0060487 lung epithelial cell differentiation Database 0
Category members GO Category GO:0060575 intestinal epithelial cell differentiation Database 0


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