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Query: S100A8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
S100A8 0 -3.190 -0.880 1.550 -3.285 -4.740

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for S100A8:


Pubmed-S100A8 »
Uniprot-S100A8 »
Biogrid-S100A8 »
ProteomicsDB-S100A8 »

Tumorportal-S100A8 »
COSMIC-S100A8 »
GenomeRNAi-S100A8 »
Genecards-S100A8


Protein-protein Interactions for S100A8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait S100A8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in S100A8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members S100_Ca-bd_sub IPR013787 0.55
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring S100A8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring S100A8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0032602 chemokine production Database 0.36
Category members GO Category GO:0070488 neutrophil aggregation Database 0.36
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0032119 sequestering of zinc ion Database 0.23
Category members GO Category GO:0035662 Toll-like receptor 4 binding Database 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0045471 response to ethanol Database 0.1
Category members GO Category GO:0002526 acute inflammatory response Database 0.09
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0050729 positive regulation of inflammatory response Database 0.08
Category members GO Category GO:0042742 defense response to bacterium Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0051493 regulation of cytoskeleton organization Database 0.04
Category members Pathway Pathway_850 PID_TOLL_ENDOGENOUS_PATHWAY 0 0
Category members GO Category GO:0001816 cytokine production Database 0
Category members GO Category GO:0002523 leukocyte migration involved in inflammatory response Database 0
Category members GO Category GO:0002544 chronic inflammatory response Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0010043 response to zinc ion Database 0
Category members GO Category GO:0030307 positive regulation of cell growth Database 0
Category members GO Category GO:0030593 neutrophil chemotaxis Database 0
Category members GO Category GO:0042060 wound healing Database 0
Category members GO Category GO:0050544 arachidonic acid binding Database 0
Category members GO Category GO:0050786 RAGE receptor binding Database 0
Category members GO Category GO:0050832 defense response to fungus Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0


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