Results for the Category
PID_TOLL_ENDOGENOUS_PATHWAY
(Pathway_850)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| HMGB1 | 2 | -1.590 | 3.400 | 2.856 | -1.899 | 0.030 | -0.792 | |
| VCAN | 1 | 0.760 | -0.630 | |||||
| VCAN | 1 | 0.760 | -0.630 | |||||
| RHOA | 0 | -0.510 | 1.370 | -0.485 | 0.532 | 0.279 | ||
| IKBKB | 0 | 0.400 | 0.610 | |||||
| S100A8 | 0 | -0.880 | 1.550 | -3.285 | -4.740 | |||
| HSPD1 | 0 | 1.020 | -0.650 | 1.151 | 0.719 | -0.757 | ||
| S100A9 | 0 | -1.350 | 2.240 | -4.360 | ||||
| CHUK | 0 | -0.480 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CHUK | Ubiquitylation | K296 | -1.637 | _GGPVDLTLK(gl)QPR_ | |
| HMGB1 | Ubiquitylation | K50 | 0.651 | _WK(gl)TMSAK_ | |
| HMGB1 | Ubiquitylation | K59 | 1.001 | 0.009 | _GK(gl)FEDMAK_ |
| HMGB1 | Ubiquitylation | K114 | 0.314 | _IK(gl)GEHPGLSIGDVAK_ | |
| HMGB1 | Ubiquitylation | K127 | 0.018 | _IKGEHPGLSIGDVAK(gl)K_ | |
| HMGB1 | Ubiquitylation | K128 | -0.407 | _K(gl)LGEMWNNTAADDKQPYEK_ | |
| HMGB1 | Ubiquitylation | K157 | 0.850 | _YEK(gl)DIAAYR_ | |
| HSPD1 | Phosphorylation | S70 | 0.210 | 0.487 | _TVIIEQSWGS(ph)PK_ |
| HSPD1 | Ubiquitylation | K82 | -0.300 | _DGVTVAK(gl)SIDLK_ | |
| HSPD1 | Ubiquitylation | K87 | -0.005 | 0.292 | _SIDLK(gl)DKYK_ |
| HSPD1 | Ubiquitylation | K130 | -0.428 | _EGFEK(gl)ISK_ | |
| HSPD1 | Ubiquitylation | K233 | 0.853 | 0.024 | _GYISPYFINTSK(gl)GQK_ |
| HSPD1 | Ubiquitylation | K292 | 0.339 | _LK(gl)VGLQVVAVK_ | |
| IKBKB | Ubiquitylation | K106 | 0.253 | _K(gl)YLNQFENCCGLR_ | |
| IKBKB | Phosphorylation | S672 | 0.670 | 0.244 | _GPVSGS(ph)PDSMNASR_ |
| RHOA | Ubiquitylation | K6 | 0.708 | _K(gl)KLVIVGDGACGK_ | |
| RHOA | Ubiquitylation | K7 | 0.708 | _K(gl)KLVIVGDGACGK_ | |
| RHOA | Ubiquitylation | K118 | -0.408 | _HFCPNVPIILVGNK(gl)K_ | |
| RHOA | Ubiquitylation | K119 | -0.408 | _HFCPNVPIILVGNK(gl)K_ | |
| RHOA | Ubiquitylation | K135 | -0.528 | -0.796 | _MK(gl)QEPVKPEEGRDMANR_ |
| RHOA | Ubiquitylation | K162 | 0.345 | 0.453 | _IGAFGYMECSAK(gl)TK_ |
| VCAN | Ubiquitylation | K98 | 2.161 | _IGQDYK(gl)GR_ | |
| VCAN | Ubiquitylation | K347 | 3.178 | _FDAYCFK(gl)R_ | |
| VCAN | Phosphorylation | S2130 | 0.600 | 0.798 | _QEIESETTS(ph)EEQIQEEK_ |
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