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Query: RTN4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RTN4 0 -0.402 0.530 -0.760 0.863 -1.844 -1.505

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RTN4 Phosphorylation T856 0.863 0.955 _ET(ph)ETFSDSSPIEIIDEFPTLISSK_
RTN4 Phosphorylation T188 0.091 0.389 _RGSSGSVDET(ph)LFALPAASEPVIR_
RTN4 Phosphorylation S184 0.143 0.327 _GSSGS(ph)VDETLFALPAASEPVIR_
RTN4 Ubiquitylation K1174 0.266 _NVK(gl)DAMAK_
RTN4 Phosphorylation S181 -0.061 -0.102 _RRGS(ph)SGSVDETLFALPAASEPVIR_
RTN4 Phosphorylation S11 -0.625 -0.783 _(ac)MEDLDQSPLVS(ph)SSDSPPRPQPAFK_
RTN4 Phosphorylation S15 -0.846 -0.788 _(ac)M(ox)EDLDQS(ph)PLVSSSDS(ph)PPRPQPAFK_
RTN4 Phosphorylation S13 -0.816 _(ac)MEDLDQSPLVSSS(ph)DSPPRPQPAFK_
RTN4 Phosphorylation S7 -1.343 _(ac)MEDLDQS(ph)PLVSSSDS(ph)PPRPQPAFK_
RTN4 Phosphorylation S107 -1.749 _GPLPAAPPVAPERQPS(ph)WDPSPVSSTVPAPSPLSAAAVSPSK_

Background Information for RTN4:


Pubmed-RTN4 »
Uniprot-RTN4 »
Biogrid-RTN4 »
ProteomicsDB-RTN4 »

Tumorportal-RTN4 »
COSMIC-RTN4 »
GenomeRNAi-RTN4 »
Genecards-RTN4


Protein-protein Interactions for RTN4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP1B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP1B3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM134C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR161 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGCZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM128 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZPLD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RTN4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Reticulon IPR003388 0.15


Protein complexes (CORUM database) featuring RTN4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1787 Nogo-potassium channel complex Database 0


Categories featuring RTN4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030334 regulation of cell migration Database 0.61
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members Pathway Pathway_557 PID_P75_NTR_PATHWAY 0 0.04
Category members GO Category GO:0021801 cerebral cortex radial glia guided migration Database 0.04
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0007413 axonal fasciculation Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0030517 negative regulation of axon extension Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0050770 regulation of axonogenesis Database 0
Category members GO Category GO:0050771 negative regulation of axonogenesis Database 0
Category members GO Category GO:0060317 cardiac epithelial to mesenchymal transition Database 0


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