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Query: RPN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPN2 0 1.132 1.000 -0.610
RPN2 0 1.132 1.000 -0.610 0.994

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPN2 Ubiquitylation K70 1.069 _K(gl)ACTYIR_
RPN2 Ubiquitylation K627 -0.931 0.454 _MLAQQAVK(gl)R_
RPN2 Ubiquitylation K403 -0.045 _VTYPAKAK(gl)_

Background Information for RPN2:


Pubmed-RPN2 »
Uniprot-RPN2 »
Biogrid-RPN2 »
ProteomicsDB-RPN2 »

Tumorportal-RPN2 »
COSMIC-RPN2 »
GenomeRNAi-RPN2 »
Genecards-RPN2


Protein-protein Interactions for RPN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP7A Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait TM9SF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUSC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPN2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring RPN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1199 Oligosaccharyltransferase complex (Stt3A variant) Database 0.78
Category members Corum 1200 Oligosaccharyltransferase complex (Stt3B variant) Database 0.78


Categories featuring RPN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_467 BIOCARTA_PROTEASOME_PATHWAY 0 0.82
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity Database 0.38
Category members GO Category GO:0008250 oligosaccharyltransferase complex Database 0.33
Category members GO Category GO:0043022 ribosome binding Database 0.33
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0000421 autophagic vacuole membrane Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0006487 protein N-linked glycosylation Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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