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BIOCARTA_PROTEASOME_PATHWAY
(Pathway_467)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PSMD11 3 -1.450 2.970 0.214 -0.184 0.431 0.233 0.368
UBE3A 2 -0.310 -0.470
PSMC4 1 -0.111 1.993 0.557
PSMA5 1 0.190 0.000 -0.828 0.332 -0.038 -1.497
PSMC3 1 -0.227 -0.102 0.203 1.582
PSMB1 0 0.310 0.480 0.145
PSMB1 0 -0.457
PSMA4 0
PSMA4 0 -0.383 -1.793 -0.367 -0.745 -0.334
PSMD8 0 -0.369 -0.795 0.980 0.270 0.207
PSMC6 0 1.170 -0.580 -0.025 0.192
PSMA3 0 -0.200 0.600 -0.457 -0.083 0.518 -0.230 -1.397
PSMB5 0 -0.630 0.970 -0.586 0.544 0.211 -0.265
PSMA6 0 -0.525 0.954 0.421 0.792 0.604
PSMA7 0 -0.630 1.250 -0.391 0.229 -0.396 -0.186
PSMA2 0 -0.344 0.665
PSMD14 0 -0.108 -0.655 0.117 -0.121 -0.010
RPN2 0 1.000 -0.610
RPN2 0 1.000 -0.610 0.994
PSMB2 0 -0.260 0.740 -0.850 1.495 0.073 -0.594 -0.213
PSMA1 0 -0.527 -0.118 -0.826 -0.205
UBA1 0 0.090 -0.310 0.251 -0.973 0.799 0.602
PSMB7 0 -0.650 1.080
PSMB7 0 -0.650 1.080 -0.459
PSMB6 0 -0.608 -0.008 -0.557 0.110
PSMB4 0 -0.430 0.532 0.468
PSMC2 0 0.410 -0.640 -0.349 -0.102 -0.395 -0.245
PSMD6 0 -0.060 0.785 -0.127 0.168 -0.285
RPN1 0 0.940 0.740 0.262 0.018 -0.781 0.557 0.400
PSMD12 0 -1.200 2.390 0.067 -0.055 0.962

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
PSMA1 Ubiquitylation K39 0.520 0.441 _QGSATVGLK(gl)SK_
PSMA1 Ubiquitylation K41 -0.003 _SK(gl)THAVLVALK_
PSMA1 Ubiquitylation K50 0.184 _THAVLVALK(gl)R_
PSMA1 Ubiquitylation K61 1.405 _AQSELAAHQK(gl)K_
PSMA1 Ubiquitylation K115 -0.377 0.087 _LVSLIGSK(gl)TQIPTQR_
PSMA1 Ubiquitylation K208 -0.998 _ETLPAEQDLTTK(gl)NVSIGIVGK_
PSMA1 Ubiquitylation K256 -2.626 _AQPAQPADEPAEK(gl)ADEPMEH_
PSMA2 Ubiquitylation K50 -1.081 _AANGVVLATEK(gl)K_
PSMA2 Ubiquitylation K51 -0.660 _AANGVVLATEKK(gl)_
PSMA2 Ubiquitylation K53 -2.456 -0.806 _QK(gl)SILYDER_
PSMA2 Ubiquitylation K64 -1.398 -0.958 _SVHK(gl)VEPITK_
PSMA2 Ubiquitylation K70 -0.584 _VEPITK(gl)HIGLVYSGMGPDYR_
PSMA2 Ubiquitylation K165 -0.769 -0.362 _ATAMGK(gl)NYVNGK_
PSMA2 Ubiquitylation K171 -0.681 -0.416 _NYVNGK(gl)TFLEK(gl)R_
PSMA2 Ubiquitylation K176 -0.342 _NYVNGK(gl)TFLEK(gl)R_
PSMA3 Ubiquitylation K43 -0.394 _CK(gl)DGVVFGVEK_
PSMA3 Ubiquitylation K57 -0.251 0.398 _LVLSK(gl)LYEEGSNKR_
PSMA3 Ubiquitylation K65 0.202 0.516 _LYEEGSNK(gl)R_
PSMA3 Ubiquitylation K174 -0.293 _QAAK(gl)TEIEK_
PSMA3 Ubiquitylation K179 -0.010 _TEIEK(gl)LQMK_
PSMA3 Ubiquitylation K183 -0.935 0.097 _LQMK(gl)EMTCR_
PSMA3 Ubiquitylation K192 -0.190 0.526 _DIVK(gl)EVAK_
PSMA3 Ubiquitylation K208 -0.430 _IIYIVHDEVKDK(gl)_
PSMA3 Phosphorylation S250 0.438 0.372 _ESLKEEDES(ph)DDDNM_
PSMA4 Ubiquitylation K176 1.345 0.502 _ATCIGNNSAAAVSMLK(gl)QDYK_
PSMA4 Ubiquitylation K180 -0.775 _QDYK(gl)EGEMTLK_
PSMA4 Ubiquitylation K199 -0.456 0.252 _VLNK(gl)TMDVSK_
PSMA4 Ubiquitylation K205 -0.630 _TMDVSK(gl)LSAEK_
PSMA4 Ubiquitylation K210 -1.092 _LSAEK(gl)VEIATLTR_
PSMA4 Ubiquitylation K222 -1.085 0.196 _ENGK(gl)TVIR_
PSMA4 Ubiquitylation K231 -0.975 -0.228 _QK(gl)EVEQLIK_
PSMA4 Ubiquitylation K238 -1.175 -0.141 _QKEVEQLIK(gl)K_
PSMA5 Phosphorylation S16 0.437 0.327 _GVNTFS(ph)PEGR_
PSMA5 Phosphorylation T55 1.635 0.149 _IT(ph)SPLMEPSSIEK_
PSMA5 Phosphorylation S56 1.475 1.212 _ITS(ph)PLMEPSSIEK_
PSMA5 Ubiquitylation K91 -0.653 _TLIDK(gl)AR_
PSMA5 Ubiquitylation K187 -0.327 -0.361 _AIGSASEGAQSSLQEVYHK(gl)SMTLK_
PSMA5 Ubiquitylation K192 0.384 0.558 _SMTLK(gl)EAIK_
PSMA5 Ubiquitylation K196 -0.899 -0.177 _EAIK(gl)SSLIILK_
PSMA5 Ubiquitylation K203 -0.437 _SSLIILK(gl)QVMEEK_
PSMA6 Ubiquitylation K45 -0.348 0.048 _GK(gl)DCAVIVTQK_
PSMA6 Ubiquitylation K55 -0.129 0.038 _GKDCAVIVTQKK(gl)_
PSMA6 Ubiquitylation K102 0.229 0.506 _YEAANWK(gl)YK_
PSMA6 Ubiquitylation K104 0.926 _YEAANWK(gl)YK_
PSMA6 Ubiquitylation K116 -1.065 -0.664 _YGYEIPVDMLCK(gl)R_
PSMA6 Ubiquitylation K170 -0.696 _CDPAGYYCGFK(gl)ATAAGVK_
PSMA6 Ubiquitylation K177 -0.464 -0.324 _ATAAGVK(gl)QTESTSFLEK_
PSMA6 Ubiquitylation K187 0.017 _QTESTSFLEK(gl)K_
PSMA6 Ubiquitylation K188 -0.004 -0.098 _QTESTSFLEKK(gl)_
PSMA7 Ubiquitylation K28 -0.017 0.505 _K(gl)GSTAVGVR_
PSMA7 Ubiquitylation K48 -0.697 _K(gl)SVAKLQDER_
PSMA7 Ubiquitylation K52 -0.191 -0.218 _SVAK(gl)LQDER_
PSMA7 Ubiquitylation K115 0.538 0.588 _YIASLK(gl)QR_
PSMA7 Ubiquitylation K157 -0.229 -0.037 _LYQTDPSGTYHAWK(gl)ANAIGR_
PSMA7 Ubiquitylation K218 -0.242 -0.114 _DQSLK(gl)ILNPEEIEK_
PSMB1 Ubiquitylation K73 0.672 0.367 _CYK(gl)LTDK_
PSMB1 Ubiquitylation K77 0.629 -0.749 _LTDK(gl)TVIGCSGFHGDCLTLTK_
PSMB1 Ubiquitylation K228 -0.675 0.154 _ICIVTK(gl)EGIR_
PSMB1 Ubiquitylation K240 -0.270 -0.706 _EGIREETVSLRK(gl)D_
PSMB2 Ubiquitylation K29 -0.187 -0.755 _VAASNIVQMK(gl)DDHDK_
PSMB2 Ubiquitylation K68 -0.570 -1.047 _NVQLYK(gl)M(ox)R_
PSMB2 Ubiquitylation K162 -0.258 -0.501 _K(gl)CLEELQK(gl)R_
PSMB2 Ubiquitylation K169 -0.265 -0.366 _KCLEELQK(gl)R_
PSMB2 Ubiquitylation K185 -1.010 -1.358 _IIDK(gl)NGIHDLDNISFPK(gl)QGS_
PSMB2 Ubiquitylation K198 -1.268 -1.381 _IIDK(gl)NGIHDLDNISFPK(gl)QGS_
PSMB4 Ubiquitylation K201 -0.945 -0.448 _EVLEK(gl)QPVLSQTEAR_
PSMB5 Ubiquitylation K91 1.377 _ATAGAYIASQTVK(gl)K_
PSMB5 Ubiquitylation K92 0.684 0.901 _ATAGAYIASQTVKK(gl)_
PSMB5 Ubiquitylation K140 -0.990 _ISVAAASK(gl)_
PSMB5 Ubiquitylation K257 -0.894 -0.379 _VSSDNVADLHEK(gl)YSGSTP_
PSMB7 Ubiquitylation K31 0.466 0.616 _NAVLEADFAK(gl)R_
PSMB7 Ubiquitylation K72 -0.218 0.284 _ATEGMVVADK(gl)NCSK_
PSMB7 Ubiquitylation K76 -0.218 0.284 _ATEGMVVADK(gl)NCSK_
PSMB7 Ubiquitylation K238 -2.530 _LDFLRPYTVPNKK(gl)_
PSMB7 Ubiquitylation K249 0.159 0.525 _CEK(gl)GTTAVLTEK_
PSMC2 Ubiquitylation K34 -0.054 0.133 _ALDEGDIALLK(gl)TYGQSTYSR_
PSMC2 Ubiquitylation K57 0.210 0.513 _QVEDDIQQLLK(gl)K_
PSMC2 Ubiquitylation K58 -0.922 0.072 _K(gl)INELTGIK_
PSMC2 Ubiquitylation K100 -0.369 -0.790 _CTK(gl)IINADSEDPK_
PSMC2 Ubiquitylation K116 0.388 0.726 _YIINVK(gl)QFAK_
PSMC2 Ubiquitylation K186 0.125 0.175 _EQIEK(gl)LR_
PSMC2 Ubiquitylation K222 -0.623 _GVLLFGPPGTGK(gl)TLCAR_
PSMC2 Ubiquitylation K248 0.800 0.448 _VIGSELVQK(gl)YVGEGAR_
PSMC2 Ubiquitylation K402 0.399 0.263 _K(gl)IATEKDFLEAVNK_
PSMC2 Ubiquitylation K407 -0.357 0.298 _IATEK(gl)DFLEAVNK_
PSMC2 Ubiquitylation K418 -0.387 0.079 _VIK(gl)SYAK_
PSMC2 Ubiquitylation K422 -0.462 -0.406 _SYAK(gl)FSATPR_
PSMC3 Phosphorylation S9 -0.089 0.162 _(ac)MNLLPNIES(ph)PVTR_
PSMC3 Ubiquitylation K16 -0.007 _QEK(gl)MATVWDEAEQDGIGEEVLK_
PSMC3 Ubiquitylation K53 1.141 _LLDSEIK(gl)IMK_
PSMC3 Ubiquitylation K56 0.171 0.893 _IMK(gl)SEVLR_
PSMC3 Ubiquitylation K70 0.813 0.938 _VTHELQAMK(gl)DK_
PSMC3 Ubiquitylation K79 0.527 _IKENSEK(gl)IK_
PSMC3 Ubiquitylation K81 0.303 _IKENSEKIK(gl)_
PSMC3 Ubiquitylation K125 0.211 0.991 _CAVIK(gl)TSTR_
PSMC3 Ubiquitylation K146 -0.149 0.433 _LK(gl)PGDLVGVNK_
PSMC3 Ubiquitylation K245 0.156 0.587 _ACAAQTK(gl)ATFLK_
PSMC3 Ubiquitylation K276 0.816 1.261 _DAFALAK(gl)EK_
PSMC3 Ubiquitylation K278 0.568 _DAFALAKEK(gl)_
PSMC3 Ubiquitylation K300 0.061 0.623 _RFDSEK(gl)AGDREVQR_
PSMC3 Ubiquitylation K372 -0.011 -0.132 _K(gl)MNVSPDVNYEELAR_
PSMC3 Ubiquitylation K431 1.026 0.632 _K(gl)KANLQYYA_
PSMC3 Ubiquitylation K432 1.026 0.798 _K(gl)ANLQYYA_
PSMC4 Phosphorylation T25 -1.198 _AQDEIPALSVSRPQT(ph)GLSFLGPEPEDLEDLYSR_
PSMC4 Phosphorylation S28 -0.962 _AQDEIPALSVSRPQTGLS(ph)FLGPEPEDLEDLYSR_
PSMC4 Ubiquitylation K80 0.193 -0.348 _EFLHAQEEVK(gl)R_
PSMC4 Ubiquitylation K125 -0.394 -0.532 _ELLK(gl)PNASVALHK_
PSMC4 Ubiquitylation K238 -0.433 _VVGSEFVQK(gl)YLGEGPR_
PSMC4 Ubiquitylation K401 -0.658 _DFEK(gl)AYK_
PSMC4 Ubiquitylation K418 0.356 0.606 _DEQEHEFYK(gl)_
PSMC6 Ubiquitylation K7 0.253 0.732 _DK(gl)ALQDYR_
PSMC6 Ubiquitylation K20 -0.044 0.744 _LLEHK(gl)EIDGR_
PSMC6 Ubiquitylation K34 -0.419 _EQLK(gl)ELTK_
PSMC6 Ubiquitylation K197 0.526 _AVASQLDCNFLK(gl)_
PSMC6 Ubiquitylation K383 0.276 -0.218 _KLESK(gl)LDYKPV_
PSMD11 Phosphorylation S14 1.600 1.518 _AQS(ph)LLSTDR_
PSMD11 Ubiquitylation K32 -0.182 _EASIDILHSIVK(gl)R_
PSMD11 Ubiquitylation K420 0.365 _VVDSLYNKAK(gl)_
PSMD12 Ubiquitylation K33 0.823 -0.095 _LPECAK(gl)LAK_
PSMD12 Ubiquitylation K147 0.758 _LTK(gl)TLATIK_
PSMD14 Ubiquitylation K154 -1.127 0.434 _GK(gl)VVIDAFR_
PSMD14 Ubiquitylation K253 0.194 -0.255 _EMLELAK(gl)NYNK_
PSMD14 Ubiquitylation K257 -0.581 -0.994 _NYNK(gl)AVEEEDKMTPEQLAIK_
PSMD6 Ubiquitylation K160 0.601 0.319 _DAMMAK(gl)AEYLCR_
PSMD6 Ubiquitylation K424 -0.180 _NWQYQETIK(gl)K_
PSMD6 Ubiquitylation K425 -0.059 0.022 _K(gl)GDLLLNR_
PSMD8 Ubiquitylation K99 -1.278 -0.146 _MYEQLK(gl)GEWNR_
PSMD8 Ubiquitylation K105 -2.675 -1.381 _K(gl)SPNLSK(gl)CGEELGR_
PSMD8 Ubiquitylation K111 -1.499 -0.536 _SPNLSK(gl)CGEELGR_
PSMD8 Ubiquitylation K138 -0.946 0.044 _LTK(gl)QQLILAR_
PSMD8 Ubiquitylation K218 -0.925 _LPAK(gl)DIQTNVYIK_
PSMD8 Ubiquitylation K281 -0.605 _AYEK(gl)ILFTEATR_
PSMD8 Ubiquitylation K297 -0.927 -0.171 _ILFFNTPK(gl)K_
PSMD8 Ubiquitylation K298 -0.927 0.026 _ILFFNTPKK(gl)_
PSMD8 Ubiquitylation K304 -2.434 _MTDYAK(gl)KR_
PSMD8 Ubiquitylation K305 -0.267 _MTDYAKK(gl)_
RPN1 Ubiquitylation K187 0.225 0.149 _NVESYTK(gl)LGNPTR_
RPN1 Ubiquitylation K258 -0.934 _HTGAVLK(gl)GPFSR_
RPN1 Ubiquitylation K517 0.437 0.831 _DISTLNSGKK(gl)_
RPN1 Ubiquitylation K538 0.059 0.574 _LK(gl)TEGSDLCDRVSEMQK_
RPN1 Ubiquitylation K553 -0.570 0.943 _VSEMQK(gl)LDAQVK_
RPN1 Ubiquitylation K564 -1.249 _ELVLK(gl)SAVEAER_
RPN1 Ubiquitylation K576 -0.148 _LVAGK(gl)LKK_
RPN1 Ubiquitylation K578 -0.355 _LK(gl)KDTYIENEK_
RPN1 Ubiquitylation K587 -1.128 _DTYIENEK(gl)LISGK_
RPN2 Ubiquitylation K70 1.069 _K(gl)ACTYIR_
RPN2 Ubiquitylation K403 -0.045 _VTYPAKAK(gl)_
RPN2 Ubiquitylation K627 -0.931 0.454 _MLAQQAVK(gl)R_
UBA1 Phosphorylation S46 0.482 0.545 _NGS(ph)EADIDEGLYSR_
UBA1 Ubiquitylation K68 0.319 _QLYVLGHEAMK(gl)R_
UBA1 Ubiquitylation K185 0.243 1.274 _GIK(gl)LVVADTR_
UBA1 Ubiquitylation K296 0.188 _GGIVSQVK(gl)VPK_
UBA1 Ubiquitylation K465 -0.360 _YDGQVAVFGSDLQEK(gl)LGK_
UBA1 Ubiquitylation K528 -0.599 0.237 _LK(gl)SDTAAAAVR_
UBA1 Ubiquitylation K593 -0.196 0.152 _K(gl)PLLESGTLGTK_
UBA1 Ubiquitylation K671 -0.518 -0.212 _QPAENVNQYLTDPK(gl)FVER_
UBA1 Ubiquitylation K746 -0.514 _QLLHNFPPDQLTSSGAPFWSGPK(gl)R_
UBA1 Ubiquitylation K802 -1.053 _AAVATFLQSVQVPEFTPK(gl)SGVK_
UBA1 Phosphorylation S835 -0.322 -0.079 _ATLPS(ph)PDKLPGFK_
UBA1 Ubiquitylation K884 -0.047 _AENYDIPSADRHKSK(gl)_
UBE3A Ubiquitylation K77 0.131 0.538 _ALELYK(gl)INAK_
UBE3A Ubiquitylation K89 -0.782 _LCDPHPSK(gl)K_
UBE3A Ubiquitylation K90 -0.804 _LCDPHPSKK(gl)_
UBE3A Ubiquitylation K112 -0.670 _GAPNNSCSEIK(gl)MNKK_
UBE3A Ubiquitylation K123 0.184 _IDFK(gl)DVTYLTEEK_
UBE3A Phosphorylation S218 3.592 3.254 _IGDSS(ph)QGDNNLQK_
UBE3A Ubiquitylation K315 -0.507 _AMSK(gl)LPLAAQGK_
UBE3A Ubiquitylation K323 -0.547 _LPLAAQGK(gl)LIR_
UBE3A Ubiquitylation K373 1.085 1.052 _NLVNDDDAIVAASK(gl)CLK_
UBE3A Ubiquitylation K552 -0.235 0.125 _LEMIAMENPADLK(gl)K_
UBE3A Ubiquitylation K553 -0.235 0.125 _LEMIAMENPADLK(gl)K_
UBE3A Ubiquitylation K824 0.226 _LK(gl)MIIAK_


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