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Query: RING1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RING1 0 5.092 -0.780 0.650 -0.374 -0.106 0.665 0.119 0.685

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RING1 Ubiquitylation K285 0.816 0.881 _YVK(gl)TTGNATVDHLSK_
RING1 Phosphorylation S140 1.059 0.697 _LHNQQALSSS(ph)IEEGLR_
RING1 Phosphorylation S254 -2.788 _GGTLGGGTLGPPS(ph)PPGAPS(ph)PPEPGGEIELVFRPHPLLVEK_
RING1 Phosphorylation S248 -2.713 -2.837 _GGTLGGGTLGPPS(ph)PPGAPS(ph)PPEPGGEIELVFRPHPLLVEK_
RING1 Phosphorylation T238 -3.017 _GGT(ph)LGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEK_
RING1 Phosphorylation S38 0.184 _TPQEAIMDGTEIAVS(ph)PR_

Background Information for RING1:


Pubmed-RING1 »
Uniprot-RING1 »
Biogrid-RING1 »
ProteomicsDB-RING1 »

Tumorportal-RING1 »
COSMIC-RING1 »
GenomeRNAi-RING1 »
Genecards-RING1


Protein-protein Interactions for RING1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCOR Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCGF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait USP7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RING1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RYBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RING1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring RING1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 929 CEN complex Database 3.25
Category members Corum 116 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.56
Category members Corum 115 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.28
Category members Corum 2945 RBP-Jkappa-RING1-KyoT2 complex Database 0.6
Category members Corum 1178 BCOR complex Database 0.34
Category members Corum 5513 Polycomb repressive complex Database 0.22
Category members Corum 1462 hPRC1L complex Database 0


Categories featuring RING1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0001739 sex chromatin Database 1.47
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members GO Category GO:0035102 PRC1 complex Database 0.62
Category members GO Category GO:0035518 histone H2A monoubiquitination Database 0.34
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048593 camera-type eye morphogenesis Database 0


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